Publications by authors named "Bardoulat Isabelle"
Article Synopsis
- ABP 501 is an adalimumab biosimilar approved for immune-mediated inflammatory diseases like rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, and a study was conducted to analyze its treatment patterns in Germany and France.
- The study included patients who started ABP 501 between October 2018 and March 2020, tracking their persistence and switching behavior based on prior experience with adalimumab products over a year.
- Results showed varying persistence rates among different diseases and countries, with experienced patients often switching back to the original adalimumab, indicating a potential nocebo effect, and highlighting the need for further research.
Article Synopsis
- - The study evaluated real-world usage of the adalimumab biosimilar ABP 501 for treating inflammatory bowel disease (IBD) by analyzing pharmacy claims data from Germany and France.
- - It included 3362 German and 733 French patients, finding that 54.4% in Germany and 65.3% in France were new to ADA products; median treatment persistence varied between groups, with ADA-naïve patients showing slightly shorter persistence times.
- - Around 53.7% of German patients and 51.0% of French patients adhered to ABP 501 during the first year, while approximately 20% switched to other therapies, often to the original adalimumab reference product
Background: Lockdowns and physical distancing have dramatically limited the circulation of SARS-CoV-2 and other common communicable infections. However, little is known about their impact on head lice and scabies.
Aim: To assess the impact of the 2020 French National lockdowns (17 March-11 May 2020, and 30 October-15 December 2020) and physical distancing recommendations (from February 2020) on the dynamics of head lice and scabies infestations.
In France, social distancing measures have been adopted to contain the spread of COVID-19, culminating in national Lockdowns. The use of hand washing, hydro-alcoholic rubs and mask-wearing also increased over time. As these measures are likely to impact the transmission of many communicable diseases, we studied the changes in common infectious diseases incidence in France during the first year of COVID-19 circulation.
View Article and Find Full Text PDFPurpose: This study evaluated the effectiveness of risk minimisation measures (RMMs) implemented following the 2014 referral for valproate in Europe.
Methods: Cross-sectional survey was conducted over 2-month period in 2016 among physicians who prescribed valproate in France, Germany, the United Kingdom, Spain and Sweden. The web-based questionnaire included five endpoints to evaluate physicians' knowledge on (a) prescribing valproate only for epilepsy and bipolar disorder in women if other treatments were ineffective or not tolerated; (b) ensuring supervision by experienced physicians while treating these conditions; (c) considering alternative treatments for women planning pregnancy, regular review of treatment needs and re-assessing the benefit-risk balance in women and girls reaching puberty; (d) informing patients about the risks of taking valproate during pregnancy and (e) advising women on effective contraception during their treatment.
Background: Moderate-to-severe allergic rhinitis (AR) may increase the risk of developing or worsening asthma, whereas treatment of AR with subcutaneously or sublingual allergen immunotherapy (SLIT) may slow this progression.
Methods: In a retrospective real-world analysis, prescription fulfilment data were gathered from French retail pharmacies between 1 March 2012 and 31 December 2016. Using linear regression analyses, patients having received at least two prescriptions of grass pollen SLIT tablets over at least 2 successive years were compared with control patients having received symptomatic medications only.
Objectives: This study aimed to describe patients treated for knee osteoarthritis between 2006 and 2013 in France and to compare the delay from diagnosis to total knee replacement between patients who received intra-articular hyaluronic acid injections and those who did not receive the injections. A second objective was to compare direct medical costs for ambulatory care between treatment groups.
Materials And Methods: Patients were selected from a representative sample of the real world administrative claims database using an algorithm developed by experts from the scientific committee of the study.
Purpose: Age-related macular degeneration (AMD) is the main cause of visual loss in the elderly population. With the use of anti-vascular endothelial growth factor, the visual outcomes of exudative AMD patients have been improved. This study was aimed at assessing the quality of life (QoL) of exudative AMD patients treated with ranibizumab and at determining its drivers in a real-life setting.
View Article and Find Full Text PDFObjectives: To estimate the daily cost of intensive care unit (ICU) stays via micro-costing.
Methods: A multicentre, prospective, observational, cost analysis study was carried out among 21 out of 23 French ICUs randomly selected from French National Hospitals. Each ICU randomly enrolled 5 admitted adult patients with a simplified acute physiology II score ≥ 15 and with at least one major intensive care medical procedure.
Background: EQOFIX is a medicoeconomic study that analyzed the health-related quality of life (HRQoL) and costs of care of the moderate and severe forms of hemophilia B, treated on demand or by prophylaxis with either plasma-derived Factor IX (pdFIX) or recombinant FIX (rFIX).
Study Design And Methods: The primary objectives were evaluations of the impact of hemophilia B on HRQoL and of the costs associated with its management. The secondary objectives were evaluations of the clinical efficacy and costs of care of pdFIX and rFIX.
Background: Few studies have evaluated the impact of gastroesophageal reflux disease symptoms on work productivity and no French data are available.
Aim: To compare the impact of typical symptoms of nocturnal vs diurnal gastroesophageal reflux disease on work productivity and daily activities.
Methods: A French prospective, multicenter, observational study was performed in primary care setting.
Background: To compare the daily costs of 3 prostaglandin analogues (bimatoprost, latanoprost, travoprost), alone, and associated with timolol in 4 European countries (Denmark, Finland, Germany, and Sweden).
Methods: Six glaucoma products were sampled by buying 5 bottles from 1 suburban pharmacy in each of the 4 countries. Drops were weighed by a single operator at 1 site according to standardized procedures.