Central retinal thickness fluctuations in patients treated with anti-VEGF for neovascular age related macular degeneration.

Purpose: This is a retrospective, single-center, non randomized interventional real life study, investigating the correlation between variability of central retinal thickness (CRT) and functional outcomes during 2 years of anti-VEGF therapy in patients treated for neovascular age related macular degeneration (nAMD).

Background: CRT fluctuations can depend on various factors such as the correct timing of injections, the therapeutic algorithm, and the number of injections (NI) performed; it is important to understand if CRT fluctuations are responsible for worse visual outcomes and consequently to identify the correct ways to avoid or reduce them.

Methods: Forty-one patients were treated for nAMD with aflibercept: 0.

Choroidal neovascular membrane following hormonal stimulation for in vitro fertilization.

Purpose: To report the onset of choroidal neovascularization (CNV) following hormonal stimulation for in vitro fertilization (IVF) in a healthy young woman.

Methods: A 31-year-old woman presented with visual impairment following hormonal stimulation for IVF. Clinical history was collected and best-corrected visual acuity (BCVA), complete eye examination, optical coherence tomography (OCT), fluorescein angiography (FA), and indocyanine green angiography were -performed.

Early onset keratectasia after photorefractive keratectomy in a case showing Vertical D topographic pattern.

Purpose: We describe a case of early onset keratectasia after photorefractive keratectomy (PRK) in a patient with Vertical D topographic pattern in one eye and suspected keratoconus in the other eye.

Methods: A 31-year-old woman underwent bilateral PRK: attempted correction was -8.00-2.

Pain during second eye cataract surgery under topical anesthesia: an intraindividual study.

Background: Aim of the study was to investigate: 1) if second eye cataract surgery under topical anesthesia is more painful than surgery on the first eye, 2) if pain experienced during the procedure on the first eye may predict the pain of the second procedure, and 3) if patients' cooperation is different between the first and the second eye procedure.

Methods: Seventy-three consecutive patients undergoing bilateral non-simultaneous cataract surgery were prospectively included in the study. Surgical technique was sutureless clear corneal phacoemulsification under topical anesthesia.

Efficacy of topical plus intracameral anesthesia for cataract surgery in high myopia: randomized controlled trial.

Purpose: To assess the efficacy of intracameral lidocaine supplementation of topical anesthesia during cataract surgery in eyes with high myopia.

Setting: Department of Ophthalmology, Ospedale San Pietro-Fatebenefratelli, Rome, Italy.

Methods: This prospective double-blind study comprised 120 highly myopic eyes with an axial length (AL) greater than 26.

Fusidic acid vs ofloxacin prophylaxis before cataract surgery.

Purpose: To evaluate the safety and efficacy of two self-administrated antibiotics in eliminating conjunctival microbial flora.

Methods: A total of 133 patients operated for cataract surgery were divided into three groups. The first group (A), 55 patients, received fusidic acid drops (1%) two times per day during the 3 days before the surgery; a second group (B), 55 patients, received ofloxacin (0.

Fusidic acid vs ofloxacin prophylaxis before cataract surgery.

Purpose: To evaluate the safety and efficacy of two self-administrated antibiotics in eliminating conjunctival microbial flora.

Methods: A total of 133 patients operated for cataract surgery were divided into three groups. The first group (A), 55 patients, received fusidic acid drops (1%) two times per day during the 3 days before the surgery; a second group (B), 55 patients, received ofloxacin (0.

Optical coherence tomography findings in a case of acute multifocal posterior placoid pigment epitheliopathy (AMPPPE).

Purpose: To report the optical coherence tomography (OCT) findings in a case of acute multifocal posterior placoid pigment epitheliopathy (AMPPPE).

Design: Case report.

Methods: A 26-year-old woman was seen for a mild loss of visual acuity in both eyes.

Optical coherence tomography findings in a case of an acute multifocal posterior placoid pigment epitheliopathy (AMPP).

Purpose: To report the optical coherence tomography (OCT) findings in a case of acute multifocal posterior placoid pigment epitheliopathy (AMPPPE).

Methods: A 26-year-old woman was seen for a mild loss of visual acuity in both eyes. The fundus examination revealed yellow-white placoid lesions in the posterior pole suggesting AMPPPE.

Lidocaine 2% gel versus lidocaine 4% unpreserved drops for topical anesthesia in cataract surgery: a randomized controlled trial.

Objective: To compare intracameral levels and clinical efficacy of lidocaine 2% gel with lidocaine 4% unpreserved drops.

Design: Double-blind, randomized, one-surgeon, controlled trial.

Participants: One hundred seven consecutive cataract cases eligible for topical anesthesia.

Development and validation of a reversed-phase liquid chromatographic method for the assay of lidocaine in aqueous humour samples.

A simple, fast and reliable reversed-phase liquid chromatographic method was developed for the assay of lidocaine in human aqueous humour samples. The samples were analysed without any preliminary treatment on a C8 column with UV detection at 225 nm. The mobile phase consisted of methanol/sodium dihydrogen phosphate (30 mM) containing sodium pentansulphonate (10 mM) adjusted to pH 2.

Corneal topography and postoperative refraction after cataract phacoemulsification following radial keratotomy.

We present one case in which phacoemulsification was performed seven years after radial keratotomy (RK). A 55-year-old military police officer had undergone successful bilateral RK for the correction of myopia seven years before he developed a cataract in his left eye. Pre-RK keratometric and refractive data and post-RK myopia reduction were not available.

Pattern electroretinogram as a function of spatial frequency after retrobulbar optic neuritis.

Steady-state (8-Hz) pattern electroretinograms in response to counterphased sinusoidal gratings of variable spatial frequency (0.6-4.8 c/deg) were recorded in 17 patients who had had retrobulbar optic neuritis in one or both eyes (23 eyes with a clinical history of optic neuritis) and in 21 age-matched normal subjects.

Macular dysfunction in multiple sclerosis revealed by steady-state flicker and pattern ERGs.

Recent evidence indicates that the 2nd harmonics of steady-state (8 Hz) electroretinograms to either sinusoidal flicker (FERG) or to counterphased gratings (PERG) presented in the macular region (9 degrees) represent different subsets of generators in the inner retina. We evaluated the steady-state macular FERG and PERG 2nd harmonics (2F and 2P, respectively) in 19 normal subjects (19 eyes) and in 23 multiple sclerosis patients (44 eyes; 25 eyes with a history of clinical optic neuritis, and 19 eyes with no history of optic neuritis, subclinical eyes). The mean 2F and 2P amplitudes were significantly reduced, as compared to controls, in both subclinical and optic neuritis eyes.