Publications by authors named "Bardo Castro"

Article Synopsis
  • Accumulation of reactive oxygen species (ROS) is crucial for plants to defend against pathogens, and it's regulated by phosphorylation and ubiquitination of the RBOHD protein in Arabidopsis.
  • Researchers identified 170 homologs of this regulatory system in tomato and examined how these homologs impact ROS production, protein stability, and disease resistance.
  • Mutational studies and CRISPR-Cas9 gene editing in tomatoes showed that altering specific residues increased ROS levels and improved resistance to certain foliar pathogens, suggesting a potential strategy for enhancing plant health without disrupting root interactions.
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Reactive oxygen species (ROS) are essential for life and are involved in the regulation of almost all biological processes. ROS production is critical for plant development, response to abiotic stresses and immune responses. Here, we focus on recent discoveries in ROS biology emphasizing abiotic and biotic stress responses.

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Production of reactive oxygen species (ROS) is critical for successful activation of immune responses against pathogen infection. The plant NADPH oxidase RBOHD is a primary player in ROS production during innate immunity. However, how RBOHD is negatively regulated remains elusive.

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CRISPR-Cas systems are adaptive immune systems that protect bacteria from bacteriophage (phage) infection. To provide immunity, RNA-guided protein surveillance complexes recognize foreign nucleic acids, triggering their destruction by Cas nucleases. While the essential requirements for immune activity are well understood, the physiological cues that regulate CRISPR-Cas expression are not.

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