Publications by authors named "Barbra Natukunda"

Article Synopsis
  • - Prostate cancer is a major health issue globally, particularly in resource-limited settings like Uganda, where late-stage diagnosis contributes to high mortality rates.
  • - A study at the Uganda Cancer Institute reviewed 300 patients with metastatic prostate cancer (mPCa) over five years, finding a significant drop in overall survival from 92.4% at one year to 45.2% at five years, with factors like high Gleason scores and fewer chemotherapy cycles linked to poorer outcomes.
  • - Most patients experienced severe lower urinary tract symptoms and a high median prostate-specific antigen (PSA) level at diagnosis, indicating advanced disease, emphasizing the need for improved early detection and treatment strategies in such settings.
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Purpose: Acute leukemias are associated with substantial morbidity and mortality, particularly in the adult population. Despite an increasing burden of acute leukemia in developing countries, there are limited data on clinical outcomes and prognostic factors in this setting. In this study, we aimed to describe the clinical characteristics, survival, and prognostic factors of adults with acute leukemia at the Uganda Cancer Institute (UCI).

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Background: We evaluated clinical outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19) in the second wave of the pandemic in a national COVID-19 treatment unit (CTU) in Uganda.

Methods: We conducted a retrospective cohort study of COVID-19 patients hospitalized at the Mulago National Referral Hospital CTU between May 1 and July 11, 2021. We performed Kaplan-Meier analysis to evaluate all-cause in-hospital mortality.

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Aim Of The Work: To assess the patient reported outcome measure (PROM) of the quality of life (QoL) of patients with autoimmune rheumatic diseases (RDs) attending two tertiary care rheumatology clinics in Uganda.

Patients And Methods: Patients with a confirmed diagnosis of RD and receiving disease modifying anti-rheumatic drugs (DMARDs) were studied. Health index and overall self-rated health status were assessed using the EuroQol 5-dimension (ED-5D-5L) questionnaire tool.

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Background: There is a scarcity of data on the burden of depression among Ugandans with rheumatoid arthritis (RA) patients. We aimed to screen for symptoms of depression, their severity and associated factors among patients with RA in Uganda.

Patients And Methods: A descriptive, cross-sectional study was conducted between September and December 2020 at Mulago National Referral Hospital (MNRH) and Nsambya Hospital.

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