Transposition of the gastroduodenal artery for vascular reconstruction of invasive lesion of the hepatic hilum due to colorectal adenocarcinoma metastasis: case report.

Colorectal cancer is one of the most prevalent malignant neoplasms in Brazil. Hepatectomy for resection of liver metastases plays an essential role in increasing disease-free survival, with the possibility of cure. The feasibility of liver resection depends on factors related to the remaining liver after surgery.

Exploring the epidermal architecture of Dasyprocta prymnolopha: A potential dermatology research model.

The agouti (Dasyprocta prymnolopha) is a medium-sized, wild rodent that is highly rustic and docile. Its size and ease of management make it a viable candidate for an alternative animal model to traditional murine subjects. However, data on the epidermal strata of agoutis are lacking, with significant uncertainties persisting regarding their skin's characterization.

Space-time analysis of work-related musculoskeletal disorders in Brazil: an ecological study.

This study aimed to analyze the incidence of work-related musculoskeletal disorders (WMSD) in Brazil from 2007 to 2019, examining the spatial, temporal, and spatiotemporal patterns of their occurrence. An ecological time series study was conducted using spatial analysis techniques. WMSD morbidity data from 2007 to 2019 were collected from the Brazilian Information System for Notificable Diseases of the Brazilian Health Informatics Department.

Synthesis of -phenyl- and -thiazolyl-1-indazoles by copper-catalyzed intramolecular -arylation of -chlorinated arylhydrazones.

The broad application of 1-indazoles has prompted the development of several approaches for the synthesis of such compounds, including metal-free, palladium-, or copper-promoted intramolecular -arylation of in situ-generated or isolated -haloarylhydrazones. Such methods mainly start from -bromo derivatives due to the better yield observed when compared to those obtained from -chloroarylhydrazones. However, the -chloroarylaldehydes and -chloroarylketones used to prepare the arylhydrazones are more commercially available and less expensive than brominated analogs.

The Compound -2-Cyano-,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases.

The compound -2-cyano-,3-diphenylacrylamide (JMPR-01) was structurally developed using bioisosteric modifications of a hybrid prototype as formed from fragments of indomethacin and paracetamol. Initially, in vitro assays were performed to determine cell viability (in macrophage cultures), and its ability to modulate the synthesis of nitrite and cytokines (IL-1β and TNFα) in non-cytotoxic concentrations. In vivo, anti-inflammatory activity was explored using the CFA-induced paw edema and zymosan-induced peritonitis models.

Basic and associated causes of schistosomiasis-related mortality in Brazil: A population-based study and a 20-year time series of a disease still neglected.

Background: Schistosomiasis is a persistent public health problem in Brazil. Regardless advances in diagnosis and mass treatment, schistosomiasis has a severe impact on morbimortality in the country and remains a neglected tropical disease. Herein, we assessed the basic and associated causes of schistosomiasis-related deaths and the temporal and spatial patterns of mortality from the disease in Brazil between 1999 and 2018.

Bolsa Família program and incomplete childhood vaccination in two Brazilian cohorts.

Objective: To estimate the effect of being a beneficiary of the Bolsa Família Program (BFP) in the vaccination of children aged 13 to 35 months.

Methods: Our study was based on all birth records of residents of Ribeirão Preto (SP) and probabilistic sampling with 1/3 of the births of residents of São Luís (MA), selecting low-income children, born in 2010, belonging to the cohorts Brazilian Ribeirão Preto and São Luís Birth Cohort Studies and eligible for the Bolsa Família program. The information of Cadastro Único (CadÚnico - Single Registry) was used to categorize the receipt of benefit from the BFP (yes or no).

Development of an Electrochemical Immunosensor for Specific Detection of Visceral Leishmaniasis Using Gold-Modified Screen-Printed Carbon Electrodes.

Visceral leishmaniasis is a reemerging neglected tropical disease with limitations for its diagnosis, including low concentration of antibodies in the serum of asymptomatic patients and cross-reactions. In this context, this work proposes an electrochemical immunosensor for the diagnosis of visceral leishmaniasis in a more sensitive way that is capable of avoiding cross-reaction with Chagas disease (CD). Crude antigens tested in the enzyme-linked immunosorbent assay (ELISA) were methodologically standardized to best engage to the sensor.

Factors associated with lack of mammography: National Health Survey, 2013.

Introduction: Mammography is the main screening test for early detection of breast cancer; however, its access is not equal for all women in Brazil. The objective of this study was to analyze the factors associated with not having this examination done in a period of less than two years in Brazil and according to macro-region, considering sociodemographic characteristics, health conditions, lifestyle, and the use of health services.

Method: Cross-sectional study using data from the National Health Survey in Brazil (Pesquisa Nacional de Saúde - PNS).

Risk Factors and Diagnosis of Diabetic Foot Ulceration in Users of the Brazilian Public Health System.

Background: An individual with diabetes mellitus (DM) has an approximately 25% risk of developing ulcerations and/or destruction of the feet's soft tissues. These wounds represent approximately 20% of all causes of hospitalizations due to DM.

Objective: To identify the factors for the development of diabetic foot ulceration (DFU) among individuals treated by the Brazilian public health system.

[Targeting and coverage of the Bolsa Família program in children from the BRISA Birth Cohorts, Ribeirão Preto (São Paulo State) and São Luís (Maranhão State), Brazil].

The aim of this cross-sectional study nested in a cohort was to describe the targeting and coverage of the Family Income program in children 13 to 35 months of age. Data were obtained from the BRISA Birth Cohorts in Ribeirão Preto, São Paulo State, and São Luís, Maranhão State, Brazil. The cohorts started in 2010 with the inclusion of all the births in Ribeirão Preto (7,794) and 5,236 in São Luís, covering a random sample of one third.

Incomplete childhood immunization with new and old vaccines and associated factors: BRISA birth cohort, São Luís, Maranhão State, Northeast Brazil.

This study estimated the percentages of incomplete immunization with new vaccines and old vaccines and associated factors in children 13 to 35 months of age belonging to a birth cohort in São Luís, the capital of Maranhão State, Brazil. The sample was probabilistic, with 3,076 children born in 2010. Information on vaccination was obtained from the Child's Health Card.

Ultrasonography of Hands and Wrists in the Diagnosis of Complications of Chikungunya Fever.

The purpose of this series was to describe the ultrasonographic and radiographic manifestations of changes to the hands and wrists in 50 patients with chronic musculoskeletal symptoms secondary to Chikungunya fever during the 2016 outbreak that occurred in Rio de Janeiro, Brazil. Most of the plain radiographs were normal (62%). The most common ultrasonographic findings were small joint synovitis (84%), wrist synovitis (74%), finger tenosynovitis (70%), and cellulitis (50%).

Ultrasound of ankles in the diagnosis of complications of chikungunya fever.

Objective: To describe the main ultrasound findings of chikungunya fever in the ankle.

Materials And Methods: This was a cross-sectional observational study involving 52 patients referred to the Hospital Universitário Pedro Ernesto and presenting with clinical and biochemical evidence of chikungunya fever. The examinations were performed by a radiologist with more than 20 years of experience in ultrasound.