Differential attainment in higher surgical training: scoping pan-specialty spectra.

Introduction: This study aimed to evaluate differential attainment during higher surgical training (HST; all specialties) related to three ethnic cohorts: White UK (WUKG), Black and Minority Ethnic UK Graduates (BMEUKG), and International Medical Graduates (IMG).

Method: Anonymised records of 266 HSTs (126 WUKG, 65 BMEUKG, 75 IMG; 7 years) in a single UK Statutory Education Body were examined. Primary effect measures were Annual Record of Competency Progression Outcome (ARCPO) and Fellowship of the Royal College of Surgeons (FRCS) pass.

Protein-based polymer liquid embolics for cerebral aneurysms.

Cerebral aneurysms (CA), an abnormal bulge in the arteries that supply blood to the brain, are prone to rupture and can cause hemorrhagic stroke. Physicians can treat CA by blocking blood flow to the aneurysmal sac via clipping of the aneurysm neck via open procedure, or endovascular occlusion of the aneurysm with embolic materials to promote thrombus formation to prevent further inflow of blood into the aneurysm. Endovascular treatment options for CA still have significant limitations in terms of safety, usability in coagulopathic patients, and risks of device migration.

Digital holographic polarimeter using dual reference beam interferometry.

An off-axis digital holographic imaging polarimeter was developed to estimate the Jones matrices of an object. The Jones vector image of the electric field returned from the object is determined from a single holographic recording using the interference between the dual, nearly orthogonal, reference beams. The technique compensates for phase variations in the optical beam paths between the recorded holograms and relaxes the need to generate orthogonal illumination polarization states.

Unconventional domain wall magnetoresistance of patterned Ni/Nb bilayer structures below superconducting transition temperature of Nb.

Scattering of spin-up and spin-down electrons while passing through a ferromagnetic domain wall (DW) leads to an additional resistance for transport current, usually observed prominently in constricted magnetic structures. In this report we use the resistance of the DW as a probe to find an indirect signatures of the theoretically predicted spin-singlet supercurrent to spin-triplet supercurrent conversion effect of ferromagnetic DWs. Here we examine the DW induced resistance in Ni stripe in a bilayer Ni/Nb geometry in the normal state and in the superconducting state of Nb.

Nanoscale Domain Wall Engineered Spin-Triplet Josephson Junctions and SQUID.

Spin-singlet Cooper pairs convert to spin-triplet Cooper pairs on passing through a magnetically noncollinear structure at a superconductor(S)/ferromagnet(F) interface. In this context, the generation of triplet supercurrents through intrinsic ferromagnetic domain walls, which are naturally occurring noncollinear magnetic features, was proposed theoretically in the past decade. However, an experimental demonstration has been lacking in the literature, particularly because of the difficulty in accessing a single domain wall, which is typically buried between two domains in a ferromagnetic material.

Anaphylactic Reaction Rates to Blue Dyes Used for Sentinel Lymph Node Mapping: Systematic Review and Meta-analysis.

Objective: The primary objective of this study was to quantify the risk of anaphylaxis to blue dyes used in SLNB for cancer. Secondary outcomes included the identification of factors that may influence this risk.

Summary Of Background Data: Blue dyes are widely used to help identify sentinel lymph nodes in oncological surgery.

Long-term seizure recurrence after eclampsia: A systematic review and meta-analysis.

Background: Seizure recurrence after a fit has implications for both individuals and healthcare providers guiding neurologic prognosis, treatment, and driving and work restrictions. A systematic review of long-term seizure recurrence after eclampsia will help to quantify recurrence risk in this setting.

Objective: To evaluate the long-term recurrence of seizures after eclampsia.

Exchange-bias nanosegregation in novel Fe Mn Al ( = -0.25, 0, 0.25) Heusler films.

Exchange-bias has been reported in bulk nanocrystalline FeMnAl, but individual thin films of this Heusler alloy have never been studied so far. Here we study the structural and magnetic properties of nanocrystalline thin films of Fe Mn Al ( = -0.25, 0 and 0.

A dual-functional Embolization-Visualization System for Fluorescence image-guided Tumor Resection.

: Intraoperative bleeding impairs physicians' ability to visualize the surgical field, leading to increased risk of surgical complications and reduced outcomes. Bleeding is particularly challenging during endoscopic-assisted surgical resection of hypervascular tumors in the head and neck. A tool that controls bleeding while marking tumor margins has the potential to improve gross tumor resection, reduce surgical morbidity, decrease blood loss, shorten procedure time, prevent damage to surrounding tissues, and limit postoperative pain.

The pathology and aetiology of subcortical clefts in infants.

In infants, traumatic surface contusions of the brain are rare but subcortical clefts or cysts, variously labelled "contusional tears", "contusional clefts", "cortical tears" or "parenchymal lacerations" have been ascribed to trauma, and are even said to be characteristic of shaking and abuse. We describe the pathology of subcortical clefts or haemorrhages in seven infants. In none were the axonal swellings characteristic of traumatic axonal injury seen in relation to the clefts.

Demonstration of stimulated photon echo isolation using interferometric cancellation.

An alternative to phase-matched angled beam spatial-spectral holographic grating geometries for separating stimulated photon echoes (SPEs) from the probing pulse is proposed and demonstrated. By use of a Mach-Zehnder geometry with inhomogeneously broadened medium in both paths, the SPE can be interferometrically isolated from the generating probe pulse. This interferometric-based technique is well suited to waveguide geometries, which have benefits for future quantum and classical optical signal processing applications such as quantum memories, correlation, and efficient cryogenic microwave-to-optical conversion.

Phase-stable, downconverting, microwave photonic link with analysis of balanced heterodyne detection intermodulation.

A coherent downconverting microwave photonic link using balanced heterodyne detection of single-sideband modulated optical signals is analyzed and demonstrated. The intermodulation analysis shows that the second-order photodetector nonlinearity can be the limiting factor in the third-order intermodulation spur performance. The link is designed to phase coherently downconvert 17 GHz of bandwidth in an extended K-band (23-45 GHz) to 1-18 GHz to match the capabilities of modern receivers.

Influence of Silica Nanoparticle Density and Flow Conditions on Sedimentation, Cell Uptake, and Cytotoxicity.

Careful evaluation of the toxicological response of engineered nanomaterials (ENMs) as a function of physicochemical properties can aid in the design of safe platforms for biomedical applications including drug delivery. Typically, in vitro ENM cytotoxicity assessments are performed under conventional static cell culture conditions. However, such conditions do not take into account the sedimentation rate of ENMs.

Spatial-spectral holographic real-time correlative optical processor with >100 Gb/s throughput.

The demonstration of an all-optical, ultra-high-speed, time-domain signal correlator based on spatial-spectral holographic (SSH) technology is described. The fully programmable signal correlator demonstration operates asynchronously and continuously on signals with up to 32 GHz of bandwidth and correlative filter length exceeding a time-bandwidth product of 10, for the equivalent of teraflop-scale processing. Experimental demonstrations are presented that show both digital and analog correlation capability using phase-shift keyed modulation formats to search plain text ASCII data sources for arbitrary phrases at continuous line rate throughputs up to 200 Gbps with minimal latency.

Current margin practice and effect on re-excision rates following the publication of the SSO-ASTRO consensus and ABS consensus guidelines: a national prospective study of 2858 women undergoing breast-conserving therapy in the UK and Ireland.

Introduction: There is variation in margin policy for breast conserving therapy (BCT) in the UK and Ireland. In response to the Society of Surgical Oncology and American Society for Radiation Oncology (SSO-ASTRO) margin consensus ('no ink on tumour' for invasive and 2 mm for ductal carcinoma in situ [DCIS]) and the Association of Breast Surgery (ABS) consensus (1 mm for invasive and DCIS), we report on current margin practice and unit infrastructure in the UK and Ireland and describe how these factors impact on re-excision rates.

Methods: A trainee collaborative-led multicentre prospective study was conducted in the UK and Ireland between 1st February and 31st May 2016.

Micro-sized tunable liquid crystal optical filters.

Liquid crystal arrayed microcavities (LCAM) is a new technology for ultra-narrow optical filtering (FWHM ∼0.1  nm) that uses picoliter volume Fabry-Perot-type optical cavities filled with liquid crystal for tuning. LCAMs are sub-nm spectral resolution filters, which utilize well-established laser writing, thin film deposition, and wafer manufacturing techniques.

Superconducting exchange coupling between ferromagnets.

Recent discoveries from superconductor (S)/ferromagnet (FM) heterostructures include π-junctions, triplet pairing, critical temperature (T) control in FM/S/FM superconducting spin valves (SSVs) and critical current control in S/FM/N/FM/S spin valve Josephson junctions (N: normal metal). In all cases, the magnetic state of the device, generally set by the applied field, controls the superconducting response. We report here the observation of the converse effect, that is, direct superconducting control of the magnetic state in GdN/Nb/GdN SSVs.

In Situ Observations of Phase Transitions in Metastable Nickel (Carbide)/Carbon Nanocomposites.

Nanocomposite thin films comprised of metastable metal carbides in a carbon matrix have a wide variety of applications ranging from hard coatings to magnetics and energy storage and conversion. While their deposition using nonequilibrium techniques is established, the understanding of the dynamic evolution of such metastable nanocomposites under thermal equilibrium conditions at elevated temperatures during processing and during device operation remains limited. Here, we investigate sputter-deposited nanocomposites of metastable nickel carbide (NiC) nanocrystals in an amorphous carbon (a-C) matrix thermal postdeposition processing via complementary in situ X-ray diffractometry, in situ Raman spectroscopy, and in situ X-ray photoelectron spectroscopy.

High power and high SFDR frequency conversion using sum frequency generation in KTP waveguides.

We characterize the intermodulation distortion of high power and efficient frequency conversion of modulated optical signals based on sum frequency generation (SFG) in a periodically poled potassium titanyl phosphate (KTP) waveguide. Unwanted frequency two-tone spurs are generated near the converted signal via a three-step cascaded three-wave mixing process. Computer simulations describing the process are presented along with the experimental measurements.

Nano-optical single-photon response mapping of waveguide integrated molybdenum silicide (MoSi) superconducting nanowires.

We present low temperature nano-optical characterization of a silicon-on-insulator (SOI) waveguide integrated SNSPD. The SNSPD is fabricated from an amorphous MoSi thin film chosen to give excellent substrate conformity. At 350 mK, the SNSPD exhibits a uniform photoresponse under perpendicular illumination, corresponding to a maximum system detection efficiency of approximately 5% at 1550 nm wavelength.

Three dimensional digital holographic aperture synthesis.

Aperture synthesis techniques are applied to temporally and spatially diverse digital holograms recorded with a fast focal-plane array. Because the technique fully resolves the downrange dimension using wide-bandwidth FMCW linear-chirp waveforms, extremely high resolution three dimensional (3D) images can be obtained even at very long standoff ranges. This allows excellent 3D image formation even when targets have significant structure or discontinuities, which are typically poorly rendered with multi-baseline synthetic aperture ladar or multi-wavelength holographic aperture ladar approaches.

Precision and accuracy testing of FMCW ladar-based length metrology.

The calibration and traceability of high-resolution frequency modulated continuous wave (FMCW) ladar sources is a requirement for their use in length and volume metrology. We report the calibration of FMCW ladar length measurement systems by use of spectroscopy of molecular frequency references HCN (C-band) or CO (L-band) to calibrate the chirp rate of the FMCW sources. Propagating the stated uncertainties from the molecular calibrations provided by NIST and measurement errors provide an estimated uncertainty of a few ppm for the FMCW system.