Publications by authors named "Barbara Silvestre Minucci"
Cardiovascular benefits of statin plus ezetimibe combination therapy versus statin monotherapy in acute coronary syndrome: a meta-analysis of randomized controlled trials.
Gustavo de Oliveira Almeida Caroline Balieiro Edmundo Damiani Bertoli Maria Eduarda Liporaci Moreira Ana Laura Soares Silva Bárbara Silvestre Minucci
Coron Artery Dis
January 2025
Background: The efficacy of adding ezetimibe to statin therapy for event reduction in patients with acute coronary syndromes (ACS) remains a topic of ongoing debate.
Methods: We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing ezetimibe plus statin versus statin monotherapy in patients with ACS. We searched PubMed, Embase, and Cochrane for eligible trials.
Cardiovascular Benefits of GLP-1 Receptor Agonists in Patients Living with Obesity or Overweight: A Meta-analysis of Randomized Controlled Trials.
Gustavo de Oliveira Almeida Thiago Faraco Nienkötter Caroline Cristine Almeida Balieiro Eric Pasqualotto Júlia Braga Cintra Bárbara Silvestre Minucci
Am J Cardiovasc Drugs
July 2024
Article Synopsis
- GLP-1 receptor agonists (GLP-1 RAs) have been shown to effectively aid in weight loss, but their impact on cardiovascular health for people with obesity or overweight is uncertain.* -
- A systematic review and meta-analysis of 13 randomized controlled trials involving over 30,000 patients found that GLP-1 RAs significantly lowered both systolic and diastolic blood pressure and reduced the incidence of myocardial infarction compared to a placebo.* -
- However, there were no significant effects noted on other cardiovascular issues like unstable angina, stroke, atrial fibrillation, or deep vein thrombosis in the same patient population.*