Publications by authors named "Barbara Senk"
Article Synopsis
- Malignant mesothelioma (MM) is a serious, asbestos-related cancer with a poor outlook, and this study focuses on how genetic variations in the AQP1 gene might affect MM risk and treatment responses.
- The research involved 231 MM patients and 316 healthy controls, looking specifically at three AQP1 genetic polymorphisms and using statistical methods to analyze their impact.
- Findings suggest that the AQP1 rs1049305 polymorphism is linked to lower MM risk and influences treatment side effects like anemia and leukopenia, highlighting AQP1's potential role in predicting who may experience more severe side effects from cisplatin cancer treatment.
Purpose: To investigate in a pilot study of genetic polymorphisms in serotonin system influencing basal- and glucose-stimulated insulin secretion in women with polycystic ovary syndrome (PCOS).
Methods: A cross-sectional study included 65 female patients with PCOS followed up at the endocrine outpatient clinic of the University Medical Center Ljubljana and a control group of 94 young healthy female blood donors. Oral glucose tolerance test was performed only in PCOS patients and basal- and glucose-stimulated blood glucose and insulin levels were measured.