Publications by authors named "Barbara Salas-Salas"
Objective: We demonstrated for the first time the safety and feasibility of escalating up to 55 Gy/11 Gy/fr/5fr in borderline (BRPC)/unresectable locally advanced pancreatic cancer (LAPC), using the standard LINAC platform. The aim of the present study is to assess for the first time the impact of this high-dose neoadjuvant stereotactic ablative radiotherapy (SABRT) protocol on tumor resectability and pathological responses.
Materials/methods: From June 2017 to December 2022, patients with BRPC/LAPC were treated with neoadjuvant chemotherapy (ChT) and SABRT-escalated doses of SIB at 45 Gy, 50 Gy, and up to 55 Gy (BED ≥ 100).
Impact of a glutamine-enriched peptide formula on gastrointestinal toxicity and on the interruption of oncologic treatment in patients with adenocarcinoma of the rectum.
Front Nutr
December 2024
Article Synopsis
- - The study aimed to compare the effects of a glutamine-enriched peptide diet (PD) versus only dietary advice (DA) on gastrointestinal toxicity and nutrition in rectal cancer patients receiving neoadjuvant chemo-radiotherapy.
- - Results showed that the PD group had significantly lower risks of diarrhea and mucositis during and after treatment, as well as fewer interruptions in therapy among Stage III and malnourished patients.
- - The conclusion highlighted the PD's protective benefits, suggesting it may improve the clinical outcomes for rectal cancer patients undergoing chemotherapy and radiotherapy.
Background: Oropharyngeal dysphagia (OD) occurs in up to 40% of head and neck cancer (HNC) patients before treatment and remains a common symptom (23-60%) after oncological treatments, leading to several consequences. Early detection is essential for effective swallowing-rehabilitation and nutritional-support. The increased radiosensitivity of tumors associated with human papillomavirus (HPV) and advances in imaging techniques have stimulated research into deintensified strategies to minimize radiotherapy (RT) side effects.
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