Long term follow-up of humoral and cellular response to mRNA-based vaccines for SARS-CoV-2 in patients with active multiple myeloma.

Long-term kinetics of antibody (Ab) and cell-mediated immune (CMI) response to full anti-SARS-CoV-2 vaccine schedule and booster doses in Multiple Myeloma (MM) patients remain unclear. We prospectively evaluated Ab and CMI response to mRNA vaccines in 103 SARS-CoV-2-naïve MM patients (median age 66, 1 median prior line of therapy) and 63 health-workers. Anti-S-RBD IgG (Elecsysassay) were measured before vaccination and after 1 (T1), 3 (T3), 6 (T6), 9 (T9) and 12 (T12) months from second dose (D2) and 1 month after the introduction of the booster dose (T1D3).

[The assessment of nurses satisfaction for an organization that values posts and professional responsibilities].

Unlabelled: To assess the effectiveness of a new organizational model for professional development, that assigns and financially rewards 12 positions that encompass specific responsibilities (such as responsible of Evidence based Nursing; expert in pressure ulcers, responsible of the newly employed nurses), nurses' satisfaction was measured.

Method: From November to December 2003 the MC Closey Muller Satisfaction Questionnaire was administered to all the nurses in service in the wards. Levels of satisfaction of nurses with and without specific responsibilities were compared.

[Evidence based nursing and distance learning in the Italian hospital S. Orsola-Malpighi].

An experience of distance learning on Evidence Based Nursing is being implemented at the Policlinico Sant'Orsola Malpighi of Bologna. Commented evidence based abstracts on nursing techniques or problems are produced by a resource group of 80 nurses who attended specific courses. An abridged version of the recommendations is distributed to the 2300 health care professionals of the hospital with information on the distance learning session that consists in reading an extended review of the literature on one of the topics chosen and in an evaluation session.