Publications by authors named "Barbara Pecoraro"
Article Synopsis
- The study examined the relationship between plasma hepcidin levels and cardiovascular risks in patients with type 2 diabetes mellitus (T2DM) over an average follow-up of 55.6 months.
- Out of 213 T2DM patients, those with higher hepcidin levels (3rd tertile) had a significantly doubled risk of experiencing adverse cardiovascular outcomes compared to those with lower levels (1st and 2nd tertiles).
- The association remained strong even after adjusting for various cardiovascular risk factors and other potential confounders, indicating that higher hepcidin could predict increased mortality and cardiovascular events in T2DM patients.
Article Synopsis
- A meta-analysis was conducted to explore the relationship between primary hypothyroidism and metabolic dysfunction-associated steatotic liver disease (MASLD), highlighting uncertainties about the risk level associated with MASLD severity.
- The study analyzed data from 28 observational studies involving approximately 76.5 million individuals, revealing that primary hypothyroidism significantly increases the risk of prevalent MASLD and worsened conditions like steatohepatitis or advanced fibrosis.
- The findings suggest a strong association between hypothyroidism and both the occurrence and severity of MASLD, but the risk of developing MASLD over time was less conclusive with marginal significance.
Background: Recent observational studies examining the association between Helicobacter pylori infection and the risk of metabolic dysfunction-associated steatotic liver disease (MASLD) have reported conflicting results. We performed a meta-analysis to quantify the magnitude of the association between H. pylori infection and the risk of MASLD.
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- The study aimed to investigate the prevalence of high-risk carotid artery plaque (HRP) in asymptomatic adults with type 2 diabetes (T2D), as well as its relationship with cardiovascular risk factors and its potential linkage to major adverse cardiovascular events (MACE).
- A retrospective analysis of 185 asymptomatic T2D patients who underwent carotid endarterectomy revealed that 67% had HRP, which was determined by specific histological features of carotid atherosclerotic plaque.
- HRP was significantly associated with factors such as diabetic complications, severe stenosis of the carotid artery, and the presence of a specific rim sign, but it did not correlate with an increased risk of major cardiovascular events. *