Publications by authors named "Barbara Medic"

Article Synopsis
  • Thromboprophylaxis is crucial for hospitalized COVID-19 patients due to frequent thrombotic events, but it raises bleeding risk; this study examines bleeding incidence, predictors, and outcomes.
  • A retrospective analysis of 4014 patients revealed that 8% experienced bleeding, with 3.2% facing major bleeding—40.1% of which were present at admission.
  • Key predictors for major bleeding included intensive care treatment, atrial fibrillation, high white blood cell counts, low hemoglobin, and a history of bleeding, with major bleeding linked to significantly higher in-hospital mortality (59.7% vs. 34.8%).
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Dyspepsia is a disorder characterized by dyspeptic symptoms which are located in the epigastrium and related to digestion of food in the initial part of the digestive system. In functional dyspepsia, unlike organic dyspepsia, there is no underlying organic disease that would cause dyspeptic symptoms. Immune and mucosal function changes, gastric dysmotility, different composition of the gastrointestinal microbiota, and altered central nervous system processing are considered responsible for the onset of the disorder.

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Background: Patients with chronic liver disease (CLD) might have an aggravated course after acquisition of coronavirus disease 2019 (COVID-19).

Aims: To analyse the outcomes of patients with CLD who were hospitalised due to COVID-19.

Methods: The medical records of 4014 patients hospitalised because of COVID-19 in a regional referral hospital over a 12-month period were analysed.

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Article Synopsis
  • A study examined liver blood test (LBT) abnormalities in COVID-19 hospitalized patients, finding that 74.9% had deranged LBTs, primarily due to elevated AST, GGT, and ALT levels.
  • Analysis showed that higher levels of these liver enzymes, particularly AST, were linked to more severe disease and higher risk of mortality after adjusting for other health factors.
  • The findings suggest that monitoring LBTs could help predict serious outcomes in COVID-19 patients.
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