Comparison of older patients with bipolar disorder and schizophrenia/schizoaffective disorder.

Objective: The aim of this cross-sectional study was to explore differences in measures of symptoms and cognition, side effects, and functional impairment between older patients with schizophrenia and bipolar disorder.

Methods: Representative samples (N = 132) of older patients (age >54 years) with either bipolar disorder or schizophrenia and schizoaffective disorder were compared on several clinical and psychosocial variables. The measures used included the Brief Psychiatric Rating Scale, The Scale for the Assessment of Negative Symptoms, the Geriatric Depression Scale, the Abnormal Involuntary Movement Scale, the Clinical Global Impression, and the Mini-Mental Status Examination.

Atypical Antipsychotics and Glucose Dysregulation: A Series of 4 Cases.

There have been reports in the psychiatric literature of the association of glucose dysregulation and diabetes mellitus with the use of atypical and typical (conventional) antipsychotics. We present a series of 4 additional cases in which psychotic disorders (DSM-IV) were treated with atypical antipsychotics, and patients subsequently developed glucose dysregulation or diabetes mellitus. The implications of these findings are discussed.

Hyperglycemia and hypertriglyceridemia in real world patients on antipsychotic therapy.

There have been recent reports in the psychiatric literature of the possible association of glucose dysregulation and diabetes mellitus with the use of atypical antipsychotics. This article describes a retrospective chart review of patients from various clinical settings, including a continuing day treatment program, two inpatient programs, and a large private practice. Information was obtained with regard to weight, fasting blood glucose, lipid profiles, EKG changes, and medical comorbidities.

Older patients with schizophrenia: nature of dwelling status and symptom severity.

Objective: This cross-sectional study enrolled elderly patients with diagnoses of schizophrenia or schizoaffective disorder.

Method: The 85 subjects were dichotomized into two groups on the basis of dwelling status: those living independently (N=35) and those living in residential settings (N=50). The groups were compared with regard to scores on the Mini-Mental State Examination (MMSE), the Brief Psychiatric Rating Scale, the Scale for the Assessment of Negative Symptoms (SANS), the Geriatric Depression Scale and by age.