Publications by authors named "Barbara Khaidakov"

Upper respiratory tract infections (URTIs) are a prevalent health issue, causing considerable morbidity. Despite the availability of conventional treatments, there is an increasing interest in natural products due to their potential antiviral and immunomodulatory benefits. This study aims to evaluate the efficacy of an ELA blend (E-, L-, A-) in preventing and alleviating the symptoms of URTIs.

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Article Synopsis
  • The study focused on the effects of the ELA blend, which includes EP, LCK, and AM, on A549 cells and a 3D model (EpiAirway™) to explore its impact on viral infections.
  • Results showed that the ELA blend reduced inflammation and viral replication by 87.5% against HCoV-OC43, suggesting its potential as a preventive or therapeutic option for viral infections.
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Type 2 diabetes, characterized by insulin resistance and impaired glucose homeostasis, is commonly managed through lifestyle interventions and medications such as metformin. Although metformin is generally well-tolerated, it may cause gastrointestinal adverse effects and, in rare cases, precipitate lactic acidosis, necessitating cautious use in individuals with renal dysfunction. Additionally, concerns regarding its impact on hepatic function have led to its discontinuation in cirrhotic patients.

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