Harvesting wind energy to detect weak signals using mechanical stochastic resonance.

Wind is free and ubiquitous and can be harnessed in multiple ways. We demonstrate mechanical stochastic resonance in a tabletop experiment in which wind energy is harvested to amplify weak periodic signals detected via the movement of an inverted pendulum. Unlike earlier mechanical stochastic resonance experiments, where noise was added via electrically driven vibrations, our broad-spectrum noise source is a single flapping flag.

Quantifying parenchymal tethering in a finite element simulation of a human lung slice under bronchoconstriction.

Airway hyper-responsiveness (AHR), a hallmark of asthma, is a highly complex phenomenon characterised by multiple processes manifesting over a large range of length and time scales. Multiscale computational models have been derived to embody the experimental understanding of AHR. While current models differ in their derivation, a common assumption is that the increase in parenchymal tethering pressure P(teth) during airway constriction can be described using the model proposed by Lai-Fook (1979), which is based on intact lung experimental data for elastic moduli over a range of inflation pressures.

Electronic and mechanical realizations of one-way coupling in one and two dimensions.

One-way or unidirectional coupling is a striking example of how topological considerations--the parity of an array of multistable elements combined with periodic boundary conditions--can qualitatively influence dynamics. Here we introduce a simple electronic model of one-way coupling in one and two dimensions and experimentally compare it to an improved mechanical model and an ideal mathematical model. In two dimensions, computation and experiment reveal richer one-way coupling phenomenology: in media where two-way coupling would dissipate all excitations, one-way coupling enables solitonlike waves to propagate in different directions with different speeds.

Experimental observation of soliton propagation and annihilation in a hydromechanical array of one-way coupled oscillators.

We have experimentally realized unidirectional or one-way coupling in a mechanical array by powering the coupling with flowing water. In cyclic arrays with an even number of elements, solitonlike waves spontaneously form but eventually annihilate in pairs, leaving a spatially alternating static attractor. In cyclic arrays with an odd number of elements, this alternating attractor is topologically impossible, and a single soliton always remains to propagate indefinitely.

Hybrid integrate-and-fire model of a bursting neuron.

We present a reduction of a Hodgkin-Huxley (HH)--style bursting model to a hybridized integrate-and-fire (IF) formalism based on a thorough bifurcation analysis of the neuron's dynamics. The model incorporates HH--style equations to evolve the subthreshold currents and includes IF mechanisms to characterize spike events and mediate interactions between the subthreshold and spiking currents. The hybrid IF model successfully reproduces the dynamic behavior and temporal characteristics of the full model over a wide range of activity, including bursting and tonic firing.