Publications by authors named "Barbara Filiks-Litwin"

Purpose: Immune thrombocytopenic purpura (ITP) is a common paediatric disease. Diagnosis of acute ITP is based on a platelet count less than 20 x 10(9)/L, with normal haemoglobin concentration and white blood cells count and absence of underlying conditions such as lymphoproliferative disorders or lupus erythematosus. The objective of this study was to present the clinical picture, the diagnostic procedures and therapeutic management of immune thrombocytopenic purpura in children treated in the Department of Paediatric Haematology and Oncology, Medical University, Lublin.

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Background: Essential thrombocythemia is a myeloproliferative disease resulting from the clonal proliferation of a multipotent myeloid stem cell with an increased platelet count in peripheral blood. In 2% of cases the cause remains unknown. It is then called idiopathic essential thrombocythemia.

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Clinical and radiological course of femoral head necrosis of known aetiology (in a boy, aged 8, with haemophilia and in a girl, aged 13, after prolonged steroid therapy) was compared with the typical course in children with Perthes disease.

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The level of selected parameters of the coagulation system and fibrynolysis (prothrombin time, partial thromboplastin time, fibrinogen level, albumin C system, V Leiden factor and III antithrombin level) in 25 children who had been treated with Perthes disease was evaluated. In three children prolonged prothrombin time occurred; in one child anomalous protein C system was noted. The remaining parameters were normal in all children.

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The purpose of the study was to estimate the urinary excretion of NAG and alpha-1M among children who suffer from proliferative blood diseases. The group of the examined children included those who went through a viral hepatitis (VH) and who are or were treated by means of cytostatic drugs. The study comprised 73 children aged from 4 to 18 (average 11.

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