Publications by authors named "Barbara Bruno Fagundes Marques"
The SARS-CoV-2 virus primarily infects salivary glands suggesting a change in the saliva metabolite profile; this shift may be used as a monitoring instrument during SARS-CoV-2 infection. The present study aims to determine the salivary metabolomic profile of patients with and post-SARS-CoV-19 infection. Patients were without (PCR-), with SARS-CoV-2 (PCR+), or post-SARS-CoV-2 infection.
View Article and Find Full Text PDFThe World Health Organization has declared the widespread spread of SARS-CoV-2 and its associated disease (COVID-19) a public health emergency. The standard gold test for detecting the virus is the RT-PCR, performed from nasopharyngeal swab (NPS) samples. However, this test may be uncomfortable for the patient and requires specific training and attire from the health professional responsible for collecting the sample.
View Article and Find Full Text PDFObjective: To evaluate the reduction in the salivary viral load using oral antiseptic mouthwashes in patients testing positive for COVID-19.
Methods: Sixty-three individuals were recruited after testing positive for COVID-19 by real-time RT-PCR assay and divided into 5 groups. Group 1 received sterile water, group 2 received 1.
Article Synopsis
- The study aimed to compare the epithelial cells from the tongues of COVID-19 patients with those without the infection, focusing on the presence of the SARS-CoV-2 Spike protein.
- It involved 24 individuals, with 14 confirmed COVID-19 cases and 10 controls, using tongue cytological smears analyzed through immunohistochemistry and light microscopy.
- Results indicated that 71% of COVID-19-positive patients had epithelial cells expressing the Spike protein, while all controls were negative, suggesting COVID-19 causes significant changes in tongue epithelial cell morphology.