Autoimmune diseases of digestive system refer to pathological conditions, caused by autoimmune mechanisms, and their etiology remains unknown. This is a group of relatively rare diseases, however, during the last years a marked tendency towards the raise in incidence andprevalence is observed, which led to an increase in number of clinical investigations on etiology, pathogenesis, and, accordingly, development of new diagnostic methods and therapies. Results of such trials shown, for example, that the pathogenesis of chronic cholestatic liver diseases is associated with nuclear receptors function, while the main etiological and pathogenic factor of inflammatory bowel diseases represents gut microbiota.
View Article and Find Full Text PDFThe authors present the results of laser-based 13C-urea breath test (13C-UBT) application in diagnostics of Helicobacter pylori-associated diseases (chronic gastritis, duodenitis, and peptic ulcer). 13C-UBT data distribution before and after eradication therapy, as well as age distribution, were obtained. Correlations between the nosological forms and the rate of contamination were established.
View Article and Find Full Text PDFEssential phospholipids (essentiale-forte) was used in combined therapy of 36 patients with pronounced circulatory insufficiency and hepatic dysfunction. A 4-6-week course of this treatment 6 weeks after its termination resulted in good subjective response, positive changes in hemodynamics, intrahepatic cholestasis, synthetic function of the liver and lipid metabolism. The drug was well tolerated.
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