[Acute radiation effects in victims of the accident at the Chernobyl nuclear power station].

Observation made over 115 patients with acute radiation sickness due to exposure to external gamma- and beta-rays confirmed high efficiency of the earlier proposed principles of prognostication of the degree of severity by clinical manifestations of the primary disease response and those of separate syndromes, using the methods of hematological and cytogenetic analyses. Out of 115 victims, 56 persons had radiation burns (RB), 17--intestinal syndrome (IS), 80--oropharyngeal syndrome (ORS), 7--interstitial radiation pneumonitis (IRP). In thanatogenesis, of prime importance were: RB (more than 40% of the body surface)--19 persons and IRP--7 persons.

[Whole-body therapeutic gamma-irradiation using a dose of 3 Gy in acute leukemia--hematologic and clinical aspects of the bone marrow syndrome].

The authors described the time course of changes in the peripheral blood of 18 patients with acute leukemia exposed to total-body single gamma-therapeutic irradiation in a dose of 3 Gy at the stage of complete remission of leukemia. Proceeding from the number of neutrophils the authors defined 3 types of hematological response to irradiation. They also described cytopenic complications and means and methods of maintenance therapy.

[Immunochemical identification and physicochemical study of the alpha 2-glycoprotein from atherosclerotically altered aortic wall].

An antigen similar in its mobility to alpha 2-globulins has been isolated from atherosclerotic aortic wall. This antigen was undetectable in other tissues by immunodiffusion technique. The antigen was identified as alpha 2-glycoprotein of an atherosclerotic aortic wall, its molecular mass was 80,000 +/- 10,000 D.

[Changes in blood immunochemical indices in atherosclerosis patients during combined diet and drug therapy].

A total of 34 patients with atherosclerosis were on a prolonged combined dietetic and drug therapy. In 6 mos improved blood serum lipid indices (a decrease in the level of total cholesterol, a decrease in the level of atherogenic beta-lipoproteins and an increase in the level of antiatherogenic alpha 1-lipoproteins) and a decrease in the serum level of alpha 2-glycoproteins of the atherosclerotically changed aortic wall were observed. A decrease in angina attacks, AP stabilization, disappearance of dyspnea in physical exercise, and a decrease in excess body mass were noted.

[Experiences in transplanting bone marrow, leukocytes and human embryonic liver cells in hemoblastosis patients].

The authors describe the experience gained with 19 allogenic and autologous transplantations of the bone marrow, peripheral blood leukocytes, embryonal liver cells of man and syngeneic transplantation of the bone marrow to 15 patients with hemoblastoses and aplastic anemia. Non-medullary toxicity of the pretransplantation conditioning of the patients was moderate and could be successfully corrected. The clinical analysis of the complications and causes of the patients' death demonstrated an evident reduction of organ lesions as a result of the use of the common methods of preventing exo- and endogenous infections and early treatment of the complications.

[Comparative immunochemical analysis of 4 soluble erythrocyte antigens in patients with coronary atherosclerosis].

Four individual soluble antigens were identified in human erythrocytes. According to the universally accepted classification these antigens were denoted as RAE-1, RAE-2, RAE-3 and RAE-4. Physico-chemical properties of the antigens were studied.

[Improved blood flow in the organs and the prevention of thrombus formation with cold].

It has been established that tissue cooling to 15-20 degrees C brings about a short-term spasm of smooth muscles of the intestine, peripheral vessels and of the visceral vessels, replaced by an appreciable spasmolytic effect at the 5th-8th minute of hypothermia. The maximal hyperemia develops by the 15th-20th minute of the cooling and persists over the whole period of the cooling. It is assumed that inhibition of oxidative phosphorylation in the mitochondria of the smooth muscles underlies the spasmolytic action of cold.

[Immunochemical study of the alpha 2-glycoprotein from the atherosclerotically altered aortic wall in the blood serum of ischemic heart disease patients].

A study was made of the level of alpha- and beta-lipoproteins, apolipoprotein H and tissue protein alpha 2-glycoprotein of the arteriosclerotically changed aortic wall in the blood serum of 129 patients with coronary arteriosclerosis, 50 patients with various diseases of the internal organs without clinical signs of arteriosclerosis and in 26 healthy patients by the immunodiffusion method using standard assays. A significant increase in beta- and alpha-lipoprotein indices was revealed in the groups of patients with coronary heart disease as compared to the healthy persons. alpha 2-glycoprotein of the arteriosclerotically changed aortic wall was undetectable in the blood serum of the healthy persons; in the group of patients without clinical signs of coronary heart disease this protein was detected in 5 patients only in the concentration of 4-8 micrograms/ml.