Publications by authors named "Barakat Z Elsaqa"
Article Synopsis
- - Cardiovascular disease is a major health issue worldwide, and patients often require warfarin, an anticoagulant that varies greatly in effectiveness among individuals, complicating treatment.
- - This study aimed to investigate the links between specific genetic variations (SNPs) and coronary heart disease, as well as their impact on warfarin dosing in patients at a clinic in Jordan.
- - The results indicated significant relationships between the studied SNPs and warfarin sensitivity and dosing variability, although no direct associations with cardiovascular disease were found, highlighting the potential for personalized medication strategies.
Type 2 diabetes mellitus (T2DM) constitutes a major portion of Jordan's disease burden, and incidence rates are rising at a rapid rate. Due to variability in the drug's response between ethnic groups, it is imperative that the pharmacogenetics of metformin be investigated in the Jordanian population. The objective of this study was to investigate the relationship between twenty-one single nucleotide polymorphisms (SNPs) in the , , and genes and their effects on metformin pharmacogenetics in Jordanian patients diagnosed with type 2 diabetes mellitus.
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