Schizophrenia Spectrum Disorders: An Empirical Benchmark Study of Real-world Diagnostic Accuracy and Reliability Among Leading International Psychiatrists.

Background And Hypothesis: Assigning a psychiatric diagnosis in real-world situations is often difficult, given that the clinical presentation does not usually conform to the list of condensed, simplified behavioral descriptors of mainstream operational taxonomies (MOT) (eg, ICD-11 and DSM-5). The goal of this study was to benchmark diagnostic accuracy and reliability on a central and severe spectrum of psychopathology (ie, the schizophrenia spectrum disorders [SSDs]), adopting a pragmatic approach as close as possible to real-world clinical settings.

Study Design: We examined the diagnostic performance of 30 international psychiatrists experts in SSD.