Evaluation of Lapatinib and Trastuzumab for Ototoxic Effects.

Objective: Trastuzumab and lapatinib are widely used chemotherapeutic agents. Our aim in this study was to assess the possible ototoxicity of these chemotherapeutic agents.

Materials And Methods: Forty-eight rats were divided into six groups: Group 1 (control, n=8) received intraperitoneal saline for 7 days.

Two rare cases of head and neck tuberculosis.

Tuberculosis is an infectious disease, which is the leading cause of mortality and morbidity and is still a serious health concern. The fact that extra pulmonary tuberculosis does not have specific examination and radiographic findings and that clinical findings vary depending on the organ in which it is detected cause diagnostic difficulties. The head and neck region is an uncommon site for tuberculosis and tuberculosis can localise in many different places of the head and neck region.

The effect of adenoid hypertrophy on tympanometric findings in children without hearing loss.

Objectives: This study aims to investigate the effects of adenoid hypertrophy on negative middle ear pressure and diagnostic efficiency of tympanogram in the detection of otitis media with effusion in children without parental suspicion of hearing loss.

Patients And Methods: Fifty-six children (26 boys, 30 girls; mean age 5.9±2.