Publications by authors named "Bappaditya Chhatui"

Background: Palliative hypofractionated radiotherapy (RT) is an effective mode of treating painful bone metastasis. While 8 Gy single fraction radiation is often effective for the same, for complicated bone metastases a protracted fractionated regimen is preferred, of which 30 Gy/10#/2weeks or 20 Gy/5#/1 week are the most common worldwide. However such schedules add to the burden of already overburdened radiation treatment facilities in a busy center, wherein alternative logistic favourable schedules with treatment on weekends are preferred.

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Article Synopsis
  • Carcinoma of buccal mucosa is a common oral cancer in India, and this study investigates whether unilateral or bilateral neck irradiation improves locoregional control in patients with well-lateralized cancers without involved nodes in the contralateral neck.
  • The study involved 48 patients, divided into unilateral and bilateral radiation treatment groups; results showed no significant difference in disease recurrence between the two groups after a median follow-up of 23 months.
  • Findings indicate that bilateral neck radiation does not have advantages over unilateral irradiation for selected patients, highlighting that it may lead to increased radiation exposure to healthy tissues without improving disease-free survival rates.
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Background: Brachytherapy for carcinoma cervix has moved from Point A based planning to optimization of dose based on HR-CTV. Guidelines have been published by GEC ESTRO on HR-CTV delineation based on clinical gynecological examination and MR sequences. These have given significant clinical results in terms of local control.

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Aims And Objective: Incidence of breast cancer is on the rise in developed as well as in developing countries. In India it has superseded cervical cancer as the commonest malignancy in women in urban areas. A lot of risk factors have been proposed from time to time that play a causative role in the natural course of this disease.

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Context: Sequential induction chemotherapy with cisplatin and 5-fluorouracil (PF) along with interferon-alpha2b and concurrent chemoradiation offers superior loco-regional control for locally advanced carcinoma of oral tongue.

Aims: The study was designed to evaluate the beneficial role of induction PF chemotherapy and interferon-alpha2b followed by chemoradiation over definitive chemoradiation only for patients with locally advanced carcinoma of oral tongue.

Settings And Design: Phase II randomized, prospective, open-labeled, single-institutional study.

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