Case report: Cervical brachytherapy technique for locally advanced cervical cancer in a patient with complete bicorporeal uterus.

Purpose: The purpose of this study was to describe an approach to cervical brachytherapy for a patient with a complete bicorporeal uterus and locally advanced cervical cancer (LACC).

Materials And Methods: The patient was a 53-year-old woman with a complete bicorporeal uterus, diagnosed with stage IIB cervical squamous cell carcinoma due to contact bleeding. The patient underwent concurrent chemoradiotherapy (CCRT), external beam pelvic radiotherapy with 45 Gy/25 fractions, and weekly cisplatin (40 mg/m).

TREM2 Deficiency Aggravates NLRP3 Inflammasome Activation and Pyroptosis in MPTP-Induced Parkinson's Disease Mice and LPS-Induced BV2 Cells.

Microglia-mediated neuroinflammation plays a crucial role in the pathogenesis of Parkinson's disease (PD). Triggering receptor expressed on myeloid cells 2 (TREM2) confers strong neuroprotective effects in PD by regulating the phenotype of microglia. Recent studies suggest that TREM2 regulates high glucose-induced microglial inflammation through the NLRP3 signaling pathway.

Parallelism error analysis and its effect on modulation depth based on a rotating parallel mirror Fourier spectrometer.

The stability of the moving mirror of a Michelson Fourier transform spectrometer (M-FTS) has a non-negligible influence on its spectral quality, which limits its application. We proposed a spectrometer scheme with a pair of rotating parallel mirrors (RPM-FTS), which has advantages of fast response and high stability. The influence of the parallelism error of parallel mirrors on interference was analyzed by establishing a rotation vector model between the parallelism error, rotation angle, and optical path.

A Hardware-Friendly High-Precision CNN Pruning Method and Its FPGA Implementation.

To address the problems of large storage requirements, computational pressure, untimely data supply of off-chip memory, and low computational efficiency during hardware deployment due to the large number of convolutional neural network (CNN) parameters, we developed an innovative hardware-friendly CNN pruning method called KRP, which prunes the convolutional kernel on a row scale. A new retraining method based on LR tracking was used to obtain a CNN model with both a high pruning rate and accuracy. Furthermore, we designed a high-performance convolutional computation module on the FPGA platform to help deploy KRP pruning models.

Predictive correction method based on deep learning for a phase compensation system with frozen flow turbulence.

We propose a deep learning method that includes convolution neural network (CNN) and convolutional long short-term memory (ConvLSTM) models to realize atmospheric turbulence compensation and correction of distorted beams. The trained CNN model can automatically obtain the equivalent turbulent compensation phase screen based on the Gaussian beams affected by turbulence and without turbulence. To solve the time delay problem, we use the ConvLSTM model to predict the atmospheric turbulence evolution and acquire a more accurate compensation phase under the Taylor frozen hypothesis.

Blind Deblurring of Remote-Sensing Single Images Based on Feature Alignment.

Motion blur recovery is a common method in the field of remote sensing image processing that can effectively improve the accuracy of detection and recognition. Among the existing motion blur recovery methods, the algorithms based on deep learning do not rely on a priori knowledge and, thus, have better generalizability. However, the existing deep learning algorithms usually suffer from feature misalignment, resulting in a high probability of missing details or errors in the recovered images.

A Hardware-Friendly Low-Bit Power-of-Two Quantization Method for CNNs and Its FPGA Implementation.

To address the problems of convolutional neural networks (CNNs) consuming more hardware resources (such as DSPs and RAMs on FPGAs) and their accuracy, efficiency, and resources being difficult to balance, meaning they cannot meet the requirements of industrial applications, we proposed an innovative low-bit power-of-two quantization method: the global sign-based network quantization (GSNQ). This method involves designing different quantization ranges according to the sign of the weights, which can provide a larger quantization-value range. Combined with the fine-grained and multi-scale global retraining method proposed in this paper, the accuracy loss of low-bit quantization can be effectively reduced.

Circ_0008068 facilitates the oral squamous cell carcinoma development by microRNA-153-3p/acylgycerol kinase (AGK) axis.

Oral squamous cell carcinoma (OSCC) is a common cancer with high recurrence, metastasis rates and poor prognosis. Circular RNAs (circRNAs) take part in regulating OSCC. Herein, we examined the role of circ_0008068 in OSCC.

Impact analysis of hydraulic loading rate on constructed wetland: Insight into the response of bulk substrate and root-associated microbiota.

Constructed wetland (CW) is an environment-friendly and low-cost technology for nutrients removal from domestic wastewater. For a well-tuned CW, hydraulic loading rate (HLR) is one of the critical factors, particularly under the challenging circumstance of more frequent heavy rainfall events brought by global warming. In this study, a comprehensive investigation was conducted to explore the influence of different HLRs on the CW's bulk substrate and root-associated microbiota aiming to yield new insight for CW management from a hybrid perspective of environmental microbiology and engineering science.

Analysis of metabolomics and transcriptomics data in head and neck squamous cell carcinoma.

Objective: Studies have shown that cancer progression of head and neck squamous cell carcinoma (HNSCC) is related with metabolic alterations. The aim of this study is to identify the clinical roles of metabolic alterations in HNSCC.

Materials And Methods: Metabolism-related genes associated with HNSCC were searched in public databases.

LncRNA XIST Inhibits the Progression of Oral Squamous Cell Carcinoma via Sponging miR-455-3p/BTG2 Axis.

Objective: Oral squamous cell carcinoma (OSCC) is one of the most common cancers, accounting for over 90% of malignant lesions in the oral cavity. Long non-coding RNAs play an important role in the development of OSCC. This study aimed to investigate the effects of lncRNA XIST on the malignant behaviors of OSCC cells and its possible molecular mechanisms.

Senkyunolide H attenuates osteoclastogenesis and postmenopausal osteoporosis by regulating the NF-κB, JNK and ERK signaling pathways.

Osteoporosis is a common disease characterized by reduced bone mineral density and impaired bone strength and is currently one of the leading causes of fracture and morbidity among the elderly worldwide. The pathological generation of osteoclasts is an important event in the development of extensive bone resorption. Thus, the development of a drug that targets osteoclasts may be beneficial in treating osteoporosis.

Resveratrol may reverse the effects of long-term occupational exposure to electromagnetic fields on workers of a power plant.

High-voltage electricity lines are known to generate extremely low-frequency electromagnetic fields (ELF-EMFs). With the process of urbanization, increasing concerns has been focused on the potentially hazardous impacts of ELF-EMF on human health, and the conclusions are controversial. Little is known about the method of prevention against ELF-EMF induced healthy problems.

Association of Random Plasma Glucose Levels With the Risk for Cardiovascular Disease Among Chinese Adults Without Known Diabetes.

Importance: Diabetes is a known risk factor for cardiovascular disease (CVD). Substantial uncertainty remains, however, about the relevance to CVD risk for blood glucose levels below the diabetes threshold.

Objective: To examine the association of random plasma glucose (RPG) levels with the risk for major CVD in Chinese adults without known diabetes.

Effects of dietary green tea polyphenol supplementation on the health of workers exposed to high-voltage power lines.

Although it has been several decades since the focus on the effect of extremely low frequency electromagnetic fields (ELF-EMF) of high-voltage power lines on human health, no consistent conclusion has been drawn. The present study aimed to investigate the change in oxidative stress after exposure to ELF-EMFs, and potential protective effects of green tea polyphenol supplementation (GTPS) on ELF-EMFs induced oxidative stress. A total of 867 subjects, including workers with or without exposure to ELF-EMFs of 110-420kV power lines, participated and were randomized into GTPS and placebo treatment groups.

[Clinical analysis of 14 cases with nasal respiratory enithelial adenomatoid hamartom].

Objective: To describe and analyze the clinical features of nasal respiratory epithelial adenomatoid hamartom and improve the levels of diagnosis and treatment.

Method: Fourteen cases of nasal respiratory epithelial adenomatoid hamartom confirmed by pathology were collected and analyzed.

Result: In 14 cases, primary complaint of Hyposmia(or Anosmia)and nasal obstruction were occured in 13 and 11 cases respectively.

[Economic burden of disease studies in patients with epilepsy].

Objective: To analyze the various factors affecting the economic burden of disease in patients with epilepsy.

Methods: This research used a multi-stage random sampling method, comprehensive intervention and without intervention of the epilepsy project group conducted a field survey of health examination among patients with epilepsy of 874 (422 cases in intervention group and 452 cases in control group) in Mengzhou, Xiuwu, Yancheng, Yuanhui, Wuyang, Linying, Shaoling, Xinye and Fangcheng. DALY indicators combined with human capital approach was used to measure the economic burden of disease in patients from two aspects of the direct economic burden and indirect economic burden.

[Investigation of occupational exposure to power frequency electromagnetic fields in workers of power grid].

Objective: To measure and assess the levels of occupational exposure to power frequency electromagnetic fields in workers of power grid.

Methods: PMM8053 electromagnetic fields measuring system with EHP-50 probe was used to measure the levels of electromagnetic fields at working place. Personal dosimeters (EMDEX LITE) were utilized to measure the individual exposure levels of power frequency magnetic field.

Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis.

Genetic variations in metabolic genes are thought to modify the metabolic process of carcinogens and are suggested to be related to cancer risk. However, epidemiological results are not always consistent. In this meta-analysis, we assessed reported studies of associations between polymorphisms of CYP2E1 RsaI/PstI and DraI, and the risk of lung cancer.

[The efficacy of half of the Global Initiative for Asthma recommended dose of inhaled corticosteroids in the management of Chinese asthmatics].

Objective: To explore the optimal doses of inhaled corticosteroids (ICS) for the management of Chinese asthmatics in order to enhance cost-effectiveness.

Methods: A randomized, paralleled and controlled multi-center study was carried out in 11 provincial hospitals. After one week run-in period when only inhaled salbutamol as needed was given, the asthmatic patients (n = 86) were divided into two groups: patients in group G (n = 42) received inhaled ICS with the doses recommended by Global Initiative for Asthma (GINA), ie, fluticasone propionate (FP) 250 microg bid for moderate asthma and 375 microg bid for severe asthma.

[Study on dynamic changes of body mass index for adults in Henan Province].

To analysis the dynamic changes of body mass index (BMI) of adults, and provide basis for health research and policy-making, using the random cluster sampling, a total of 480 households (urban 80, suburban 80, county neighboring communities 80, rural 240) in 24 different sites were selected. The adults of selected households were subjects. Data on height, body weight and household income etc were collected in autumn of every surveying year.