Publications by authors named "Baoyong Lai"
Article Synopsis
- Triple-negative breast cancer (TNBC) presents significant treatment challenges due to high recurrence rates and absence of known therapeutic targets; however, tumor-infiltrating lymphocytes (TILs) have been associated with better survival rates in TNBC cases.
- A unique case of TNBC, named Tall Cell Carcinoma with Reversed Polarity (TCCRP), was studied, revealing low TILs infiltration but a good prognosis in a 54-year-old woman despite being triple-negative for common markers.
- The findings suggest TCCRP may have distinct biological behaviors with low TILs, possibly due to the presence of Cancer-Associated Fibroblasts (CAF) that could hinder anti-tumor immunity, warrant
Background: Moderate to severe breast pain has major effects on the quality of life for patients. Patent Chinese medicines are widely used in the treatment of breast pain due to their stable dosage form and good efficacy.
Objective: To evaluate the beneficial effects and safety of Hongjin Xiaojie Capsule (HJXJC), a Chinese patent medicine, for the treatment of cyclical breast pain.
Objective: This study aims to investigate physicians' familiarity and awareness of four diabetes guidelines and their practice of the recommendations outlined in these guidelines.
Design: A cross-sectional study.
Setting: An online questionnaire survey was conducted among physicians affiliated with the Specialist Committee for Primary Diabetes Care of China Association of Chinese Medicine, using the snowball sampling method to ensure a broader representation of physicians.
Objective: To systematically evaluate the effect and safety of compound Kushen injection (CKI) as an add-on treatment on the treatment for breast cancer.
Methods: We searched eight major electronic databases from their inception to November 1, 2021, for randomized clinical trials (RCTs) comparing CKI plus chemotherapy with chemotherapy alone. Primary outcomes included objective response rate (ORR) and disease control rate (DCR), health-related quality of life (HRQoL), progression-free survival (PFS), and overall survival (OS).
Breast cancer is one of the cancers with the highest incidence among women. In the late stage, cancer cells may metastasize to a distance, causing multiple organ diseases, threatening the lives of patients. The detection of lymph node metastasis based on pathological images is a key indicator for the diagnosis and staging of breast cancer, and correct staging decisions are the prerequisite and basis for targeted treatment.
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- The study investigates the risk factors for lactation mastitis (LM) among postpartum women in China, analyzing 14 studies with a total of 8,032 participants to provide a comprehensive overview of this health issue.
- Significant risk factors identified include improper milking methods, repeated milk stasis, and the early postpartum period, each associated with high odds ratios indicating their impact on developing LM.
- Findings emphasize the need for awareness and preventive measures, as approximately 3% to 33% of women experience LM, and understanding these risk factors can enhance maternal health and breastfeeding practices.
To present the evidence of the therapeutic effects and safety of Chinese herbal medicine (CHM) used with or without conventional western therapy for COVID-19. Clinical studies on the therapeutic effects and safety of CHM for COVID-19 were included. We summarized the general characteristics of included studies, evaluated methodological quality of randomized controlled trials (RCTs) using the Cochrane risk of bias tool, analyzed the use of CHM, used Revman 5.
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- The study aimed to evaluate the effectiveness and safety of Compound Glycyrrhizin Injection (CGI) in treating liver damage in chronic hepatitis B (CHB) by analyzing various research databases and employing randomized controlled trials (RCTs) for assessment.* -
- A total of 18 RCTs were analyzed, which included 1,915 participants. The findings indicated that CGI showed better overall clinical effectiveness compared to the control group; however, it did not significantly increase normalization rates of liver enzymes (ALT and AST) compared to other treatments.* -
- Ultimately, when CGI was combined with other common medications, it proved more effective in lowering liver enzyme levels and enhancing clinical effectiveness than diammonium glycyrrhizinate
Objective: To develop and validate Clinical Diversity In Meta-analyses (CDIM), a new tool for assessing clinical diversity between trials in meta-analyses of interventions.
Study Design And Setting: The development of CDIM was based on consensus work informed by empirical literature and expertise. We drafted the CDIM tool, refined it, and validated CDIM for interrater scale reliability and agreement in three groups.
To systemically evaluate the clinical efficacy and safety of Hongjin Xiaojie Capsules for hyperplastic disease of breast(HDBA), so as to provide the evidence for its clinical application. The inclusion criteria are the RCT of single administration of Hongjin Xiaojie Capsules for treatment of HDBA. We retrieved following databases(CNKI, WanFang, VIP, SinoMed, Cochrane Library and PubMed) from their inception to October 1, 2019.
View Article and Find Full Text PDFBackground: Breast pain is one of the most common breast disorders, affecting 41%-69% women in the clinical populations. Chinese herbal medicine (Rupi Sanjie, RPSJ) capsule has been recommended to be commonly used for breast pain in China. This review aimed to systematically collect latest evidence and critically evaluate the eff ;ectiveness and safety of RPSJ capsule for breast pain.
View Article and Find Full Text PDFBackground: Pediatric tuina is used to prevent and treat disease by employing various manipulative techniques on specific parts of the body, appropriate to the child's specific physiological and pathological characteristics.
Objective: To evaluate the effects and safety of pediatric tuina as a non-pharmaceutical therapy for anorexia in children under 14 years.
Methods: Randomized controlled trials (RCTs) comparing pediatric tuina with medicine for anorexia were included in this review.
Objective: This bibliometric study aimed to systematically and comprehensively summarize the volume, breadth and evidence for clinical research on Qigong. And this bibliometric analysis also can provide the evidence of this field.
Design: Bibliometric analysis.
The objectives of this study are to conduct a comprehensive literature search and bibliometric analysis to identify the breadth and volume of pharmacological and clinical studies on pine pollen () and to identify the potential effects and the use of pine pollen. Three Chinese electronic databases and two English electronic databases were searched for pharmacological and clinical studies on pine pollen. Data were extracted and analyzed and included publication year, authors, study type, pharmacological research topics or clinical diseases/conditions, usage and type of preparation, authors' conclusions, and adverse effects.
View Article and Find Full Text PDFObjectives: To investigate the consistency of adverse events (AEs) and adverse drug reactions (ADRs) reported in the literature, monitoring and social media data.
Methods: Using one Chinese patent medicine-Cordyceps sinensis extracts (CSE) as an example, we obtained safety data from the national monitoring system (July 2002 to February 2016), literature (up to November 2016) and social media (May 2019). For literature data, we searched the Chinese National Knowledge Infrastructure Database (CNKI), WanFang database, Chinese Science and Technology Periodical Database (VIP), Chinese Biomedical Literature Database (SinoMed), PubMed, Embase and the Cochrane Library.
Objective: To explore the influence of patients' participation in and completing the acupuncture clinical trials through a cross-sectional survey. In addition, we explored potential factors involved in improving patient's compliance to treatment, thus enhancing the quality of acupuncture clinical studies.
Methods: A survey was conducted at outpatient department of acupuncture and metabolic diseases in two hospitals in Beijing.
Article Synopsis
- The study assessed the effectiveness and safety of pediatric Tui Na as a treatment for acute diarrhea in children under 5 by comparing it to conventional medicine like montmorillonite and probiotics.
- Researchers conducted a systematic review and meta-analysis on 26 randomized clinical trials involving 2410 children and used specific criteria to define clinical cure and measure diarrhea duration.
- Results showed that pediatric Tui Na significantly improved clinical cure rates compared to conventional treatments, especially after three and six sessions, although many studies had risks of bias.
Background: Both cupping therapy and acupuncture have been used in China for a long time, and their target indications are pain-related conditions. There is no systematic review comparing the effectiveness of these two therapies.
Objectives: To compare the beneficial effectiveness and safety between cupping therapy and acupuncture for pain-related conditions to provide evidence for clinical practice.