Case Report: A case of Dubin-Johnson syndrome in a newborn.

Background: Dubin-Johnson Syndrome (DJS) is a rare autosomal recessive genetic disorder, with most cases presenting in adolescence, but rare in newborns.

Objective: To investigate the clinical characteristics and treatment outcomes of DJS in a newborn.

Methods: We present the clinical features of a newborn diagnosed with DJS through molecular genetic testing.

Pediatric perforated appendicitis diagnosis based on the C-reactive protein/prealbumin ratio.

Pediatric perforated appendicitis, prone to multiple complications, necessitates identifying potential serum biomarkers for early diagnosis and intervention. A cross-sectional study was conducted on patients under 16 with acute appendicitis, admitted to Hainan Women and Children's Medical Center from January 2019 to July 2023. The patients were categorized into perforated and non-perforated groups.

Circ-PRMT5 stimulates the proliferative ability in Wilms' tumor through the miR-7-5p/KLF4 axis.

CircRNAs are extensively discovered in mammals and they are closely linked to tumor cell behaviors. This study aims to detect the expression pattern of circ-PRMT5 in Wilms' tumor and its ability in influencing tumor development. Circ-PRMT5 levels in Wilms' tumor samples were detected.