SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis.

Keratinocyte hyperproliferation is a key pathogenic factor in psoriasis. However, the mechanisms that regulate keratinocyte hyperproliferation in this condition remain unclear. Here, we found that SLC35E1 was highly expressed in keratinocytes of patients with psoriasis and that Slc35e1 mice displayed a less severe imiquimod (IMQ)-induced psoriasis-like phenotype than their wild-type siblings.

Effect of D-Limonene Nanoemulsion Edible Film on Banana ( Linn.) Post-Harvest Preservation.

D-limonene (4-isopropenyl-1-methylcyclohexene) is an important compound in several citrus essential oils (such as orange, lemon, tangerine, lime, and grapefruit). It has been used as a flavoring agent and as a food preservative agent, with generally recognized as safe (GRAS) status. D-limonene has been well-studied for its anti-inflammatory, antioxidant, anti-cancer, and antibacterial properties.

Both Prevalence and Severity of Pruritus are Associated with Age in Chinese Patients with Skin Diseases.

Background: Although the characteristics of pruritus in some skin diseases are documented, characteristics of pruritus related to gender-, age-, and skin disorder have not yet been well defined.

Objective: To characterize dermatosis-associated pruritus in Chinese patients.

Methods: A cross-sectional study was carried out in a single center.

Prevalence and Severity of Dermatological Condition-Associated Skin Pain in the Chinese.

Background/aim: Although the characteristics of cutaneous sensory symptoms in the general population have been documented, dermatological condition-associated skin pain has not been characterized yet. In the present study, we aimed to characterize dermatological condition-associated skin pain in the Chinese.

Subjects And Methods: A questionnaire was given to outpatients to identify self-proclaimed skin pain at our dermatology clinic.

Gender-related characterization of sensitive skin in normal young Chinese.

Background: While clinical signs, symptoms, as well as etiology of sensitive skin in general populations have been extensively studied over the last decades, characteristics of sensitive skin in normal subjects, particularly gender-related characteristics, still remain unknown.

Objective: In the present study, we characterize facial sensitive skin in normal young Chinese.

Subjects And Methods: A questionnaire was given to each participant aged 10-30 years.