Kinesin Family Member C1: Function in liver hepatocellular carcinoma and potential target for chemotherapeutic.

MiR-105 exerts inhibitory effects on the development and progression of various cancers, including breast cancer, lung cancer, and gastric cancer. Through GEO data analysis, we observed decreased expression of miR-105 in liver cancer tissues compared to adjacent tissues. Furthermore, miR-105 downregulates KIFC1 expression levels by targeting its 3' UTR.

[Lead impairs ability of learning and memory and affects expression of synaptosomal-associated protein-25 in hippocampus of offspring].

Objective: To find the effects of lead taken by pregnant mice on learning and memory and the expression of synaptosomal-associated protein (SNAP)-25 mRNA and protein, in order to reveal the mechanism of neurotoxicity induced by lead.

Methods: Lead exposure was conducted through freely drinking the corresponding lead acetate solutions with dosages of 0.3, 1.