Three-dimensional molar enamel thickness and distribution patterns in Late Miocene Lufengpithecus lufengensis from Shihuiba, Southwest China.

Enamel thickness and distribution provide dietary insights in hominoids. Yet, three-dimensional (3D) enamel analysis of the Late Miocene Lufengpithecus from southwest China is lacking. We digitally reconstructed 68 unworn or lightly worn Lufengpithecus (L.

Flipped classroom assisted by Rain Classroom for anatomy practical classes: Challenges and opportunities of anatomy education.

Anatomy practical classes are an essential part of learning human anatomy. The flipped classroom teaching model has been used in medical education in recent years. However, its precise impacts on anatomical knowledge acquisition and learning outcomes remain controversial.

Metformin Inhibits Lipid Droplets Fusion and Growth via Reduction in Cidec and Its Regulatory Factors in Rat Adipose-Derived Stem Cells.

Metformin is still being investigated due to its potential use as a therapeutic agent for managing overweight or obesity. However, the underlying mechanisms are not fully understood. Inhibiting the adipogenesis of adipocyte precursors may be a new therapeutic opportunity for obesity treatments.

Ups and downs: The PPARγ/p-PPARγ seesaw of follistatin-like 1 and integrin receptor signaling in adipogenesis.

Objective: Although Follistatin-like protein 1 (FSTL1), as an "adipokine", is highly expressed in preadipocytes, the detail role of FSTL1 in adipogenesis and obesity remains not fully understood.

Methods: In vitro differentiation of both Fstl1 murine embryonic fibroblasts (MEFs) and stromal vascular fraction (SVF) were measured to assess the specific role of FSTL1 in adipose differentiation. Fstl1 adipocyte-specific knockout mice were generated to evaluate its role in obesity development.