Publications by authors named "Baolian Huang"
Article Synopsis
- Oral delivery of proteins (like medicines) is tricky because strong stomach acids and enzymes can break them down.
- Scientists suggest using a special clay called montmorillonite (MMT) to help deliver these proteins safely to the gut without breaking them.
- This MMT can help keep the proteins active and also improve gut health by promoting helpful bacteria that boost the immune system.
Article Synopsis
- Oncolytic bacteria, particularly attenuated Salmonella typhimurium (VNP20009), show promise as a targeted therapy for tumors, but balancing effectiveness and safety remains a challenge.
- A new delivery system enhances the tumor-targeting capability of VNP20009 by loading it into neutrophils, improving its therapeutic effects in melanoma lung metastasis.
- The addition of a PD1 nanobody to this system boosts immune responses by activating dendritic cell maturation and enhancing the activation of CD4 and CD8 T-cells, leading to improved overall treatment efficacy.
A bacteria-based system expressing anti-TNF-α nanobody for enhanced cancer immunotherapy.
Signal Transduct Target Ther
April 2023
The bamboo aphid, Pseudoregma bambucicola, is an important insect pest of bamboo that affects normal bamboo growth and induces sooty molds. The control of P. bambucicola involves the application of chemicals, such as imidacloprid, to which many species are resistant.
View Article and Find Full Text PDF