Background: To examine standardized uptake value of the primary lesion (pSUVmax) and tumor markers (TMs) for clinically predicting distant metastasis in novo lung adenocarcinoma.
Methods: The current retrospective observational study examined individuals diagnosed with de novo lung adenocarcinoma at Shanxi Cancer Hospital between February 2015 and December 2019.
Results: Totally, 532 de novo lung adenocarcinoma cases were included.
Background: To evaluate the prompting value of thyroid transcription factor 1 (TTF-1) and Napsin A for the status of epidermal growth factor receptor () mutations in an independent cohort of lung adenocarcinomas (LUADs) when genetic testing is unavailable.
Methods: In this study, 976 untreated primary LUADs were retrospectively reviewed. The clinical and pathological data, including age, gender, smoking history, predictive values of TTF-1 and Napsin A, status, and tumor-node-metastasis (TNM) stage were obtained through medical records available in Shanxi Province Cancer Hospital.
Background: A non-invasive, simple, and convenient method to evaluate the presence of epidermal growth factor receptor () mutations is important for initial treatment decisions in lung adenocarcinoma.
Methods: We retrospectively reviewed 297 untreated primary lung adenocarcinoma patients with exact status. Based on their status, the patients were divided into a mutant-type group (138 patients) and wild-type group (159 patients).
Background: This study was to investigate the influence of GSTP1 gene polymorphism on the clinical outcomes of patients with advanced non-small-cell lung cancer (NSCLC) receiving first-line bevacizumab plus chemotherapy regimen.
Methods: A total of 128 patients with advanced NSCLC who were administered with bevacizumab-based first-line regimens were recruited in this study. Available blood specimen and peripheral blood mononuclear cells (PBMCs) of the patients were obtained for the analysis of polymorphism and GSTP1 gene mRNA expression, respectively.
Background: No tumor biomarker (TM) is available for de novo metastatic lung adenocarcinoma.
Objective: To examine the serum levels of carcinoembryonic antigen (CEA), cytokeratin-19 fragments (CYFRA21-1), neuron-specific enolase (NSE), carbohydrate antigen (CA) 19-9, CA125, tissue polypeptide antigen (TPA), tissue polypeptide specific antigen (TPS), and lactate dehydrogenase (LDH) to predict de novo metastatic lung adenocarcinoma.
Methods: This was a retrospective study of geriatric (⩾ 60 years of age) patients with lung cancer diagnosed at Shanxi Cancer Hospital from 02/2012 to 12/2017.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2016
Objective: To compare the cytotoxicity of ex vivo expanded NK cells detected by flow cytometry with 3 different staining methods.
Methods: NK cells were collected from peripheral blood on the 17 day after culture. The cultured cells were divided into 3 groups: group A , B, and C.