Publications by authors named "Baojiang Liu"

Pharmacotherapy is crucial for advanced hepatocellular carcinoma (HCC). The multi-kinase inhibitor donafenib offers superior survival benefits over sorafenib. Donafenib has first-line status, but there is limited research for combination therapies with this anticancer agent.

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Photonic crystal hydrogels (PCHs) are innovative materials that translate imperceptible deformations and humidity changes into visible colors, broadening the applications of photonics in bioengineering and smart materials. To overcome poor mechanical properties of traditional PCHs limited by weak intermolecular forces, we designed a PCH with a dual-network framework comprising N-isopropylacrylamide-co-acrylamide (NIPAM-co-AM) and biomass lotus root starch (LR). Since LR is rich in hydroxyl groups, it can undergo molecular linkage entanglement with the NIPAM-co-AM hydrogel matrix, forming hydrogen bonds that significantly enhance the mechanical properties of the PCH.

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Solar energy, with its sustainable properties, has garnered considerable attention for its potential to produce green electricity and clean water. This paper proposes a multistage energy transfer co-generation system (MWCNTs-covered thermoelectric module with aerogel and cooler, AC-CTEM) combining power generation and evaporative cooling. On the light-absorbing surface, the hot side of a thermoelectric module is covered with a hydrophobic coating made of PDMS and MWCNT.

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Although the presence of the built-in electric field will solve the problem of carrier complexation in photocatalytic systems to some extent. However, free carriers will quickly shield the stabilized electric field and lose its effect. Therefore, how to introduce the dynamic piezoelectric field into the photocatalytic system has become an imminent problem.

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A biomass CS/CNTs@MTMS (MCCS) aerogel with both aligned channel network, superhydrophobicity, and photothermal conversion ability was prepared by a green and facile strategy of directed freeze-drying and chemical vapor deposition using chitosan (CS), carbon nanotubes (CNTs), and methyltrimethoxysilane (MTMS) as the building materials. Capacity to adsorb a large variety of oils and organic solvents, with an adsorption capacity of up to 34-83 g/g. After 10 cycles, the adsorption capacity of MCCS remained at 94 % of the initial capacity, providing excellent reusability.

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Article Synopsis
  • Traditional electromagnetic shielding materials face challenges like excessive fillers and poor mechanical properties, which make them impractical for real-world use.
  • A new hydrogel with a honeycomb-like structure made from Polyvinyl alcohol (PVA) and chitosan (CS) enhances mechanical strength and flexibility, aided by MXene additives for improved electromagnetic shielding performance.
  • The developed hydrogel can also function as a rapid-response sensor, showing promising sensitivity and quick signal processing, making it ideal for wearable technology and pressure-sensitive applications.
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  • The study introduces a new freeze-resistant conductive hydrogel called PHEA-NaSS/G, which maintains its properties in extreme environments by modifying hydrogen bonds through a special solvent system.
  • This hydrogel boasts impressive mechanical strength (174 kPa) and flexibility (2105% strain), making it suitable for monitoring human motion and demonstrating excellent sensing capabilities.
  • Additionally, it can accurately recognize handwritten English letters using advanced algorithms, suggesting valuable applications in areas like soft robotics and health monitoring.
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  • Hydrogels are essential for wearables due to their flexibility and sensitivity, but they challenge to maintain efficiency under varying humidity and temperature.
  • A dual network hydrogel using tannic acid, polyacrylamide, and sodium carboxymethylcellulose was developed, enhanced with green solvents for improved water retention and mechanical consistency.
  • The composite hydrogel exhibits long-term stability and high sensitivity as a strain sensor, making it suitable for smart flexible electronics in tough environmental conditions.
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With the increase of oily wastewater discharge and the growing demand for clean water supply, high throughput green materials for oil-water separation with anti-pollution and self-cleaning ability are urgently needed. Herein, the polysaccharide-based composite aerogels of CMC/SA@TiO-MWCNTs (CSTM) with fast photo-driven self-cleaning ability have been prepared by a simple freeze-drying and ionic cross-linking strategy. The introduction of TiO /MWCNTs nanocomposites effectively improves the underwater oleophobic and mechanical properties of polysaccharide aerogels and enables their photo-driven self-cleaning ability for efficient oil-water separation and purification of complex oily wastewater.

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Purpose: Recently, hepatic arterial infusion chemotherapy (HAIC) has also gained popularity for hepatocellular carcinoma (HCC). Several studies have compared HAIC and Transarterial chemoembolization (TACE). However, comparisons between TACE plus HAIC and HAIC are rarely reported.

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  • This study aimed to identify risk factors for severe hypersensitivity reactions to oxaliplatin (OXA) during hepatic arterial infusion chemotherapy (HAIC) in gastrointestinal cancer patients.
  • Out of 84 patients who experienced hypersensitivity, 27.4% had severe reactions, and a study of retreatment showed a recurrence rate of 51.9% for those with non-severe reactions.
  • The analysis found that higher doses of OXA significantly increased the risk of severe reactions, highlighting the need for caution with dosing during treatment.
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Background And Aim: Transarterial chemoembolization combined with hepatic arterial infusion chemotherapy (TACE-HAIC) has shown encouraging efficacy in the treatment of unresectable hepatocellular carcinoma (HCC). We aimed to develop a novel nomogram to predict overall survival (OS) of patients with unresectable HCC treated with TACE-HAIC.

Methods: A total of 591 patients with unresectable HCC treated with TACE-HAIC between May 2009 and September 2020 were enrolled.

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One of the most effective ways to address the problems of low solar spectrum utilization in photocatalysis and the high cost of persulfate activation technology is to create a cost-effective synergistic photothermal persulfate system. In this work, a brand-new composite catalyst called ZnFeO/FeO@MWCNTs (ZFC) was developed to activate PDS (KSO) from the aforementioned basis. ZFC's surface temperature could unbelievably reach 120.

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The photocatalytic property of available semiconductor catalysts still suffers from some urgent problems, such as the high excitation energy, easy agglomeration of powders, or weak recycling property. Therefore, developing novel visible light-supported catalysts and catalyst loading have aroused great attention recently. In this work, a novel AgPO/BiVO/MWCNTs@Cotton functional fabric was prepared by introducing AgPO as a plasma resonance photocatalyst and MWCNTs with cotton as composite substrates.

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We synthesized an MBCN (MOF-Fe/Co nanosheets/boron-doped g-CN) composite catalyst for enhancing the concurrent photocatalytic-persulfate activation (CPPA) system and achieved efficient degradation of antibiotics. The role of MOF-Fe/Co is to activate persulfate, while boron-doped g-CN can generate photogenerated electrons for the reduction of Co/Fe to enhance the regeneration of the active center. The rate constant for Tetracycline degradation by the CPPA system was 4.

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Introduction: Hepatocellular carcinoma (HCC) may occur with several simultaneous tumor foci in the liver (multifocal HCC). Molecular biology indicated that the larger the distance between two tumor nodules, the more those two nodules differed in their genetic composition. Therefore, we explored whether the overall survival (OS) of patients with HCC depends on the mutual distance of the HCC nodules.

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Recent progress in photocatalytic hydrogen generation reaction highlights the critical role of co-catalysts in enhancing the solar-to-fuel conversion efficiency of diverse band-matched semiconductors. Because of the compositional flexibility, adjustable microstructure, tunable crystal phase and facet, cobalt-based co-catalysts have stimulated tremendous attention as they have high potential to promote hydrogen evolution reaction. However, a comprehensive review that specifically focuses on these promising materials has not been reported so far.

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Article Synopsis
  • The study examined the effectiveness and safety of combining hepatic artery infusion chemotherapy (HAIC) with anti-PD-1 immunotherapy and tyrosine kinase inhibitors (TKIs) in treating advanced hepatocellular carcinoma (HCC).
  • A total of 27 patients were analyzed, with a median follow-up of 12.9 months, showing a median progression-free survival of 10.6 months, an objective response rate of 63.0%, and a disease control rate of 92.6%.
  • No patients experienced treatment-related deaths, indicating that the combined therapy was both effective and safe for advanced HCC.
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In this work, a Z-scheme heterojunction of BiOIO/MIL-88B was constructed via two steps solvothermal method. Various characterization techniques showed that this Z-scheme heterojunction is an effective strategy to promote spatial charge separation, and the catalytic performance was evaluated by degrading simulated organic pollutants. Herein, the BiOIO/MIL-88B composites exhibited an exceptional removal rate for Reactive Blue 19 and tetracycline hydrochloride (TC) under visible light irradiation, which was approximately 3.

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Developing photocatalysts that are inexpensive and efficient in degrading pollutants are essential for environmental remediation. Herein, a novel system of perylene diimide (PDI)/CuS p-n heterojunction was synthesized by a two-step self-assembly strategy for removal of tetracycline in waste water. Results showed that PDI/CuS-10% exhibited highest photocatalytic behavior.

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Purpose: To investigate the effects of ablation time and distance between the radiofrequency ablation (RFA) electrode tip and a large vessel on the ablation zone in beagle livers.

Methods: Sixty-one percutaneous RFA coagulation zones were created near large vessels in 10 beagle livers . The ablated lesions were divided into four groups based on ablation time and distance between the electrode tip and a large vessel (group A, 3 min 0.

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  • Patients with hepatocellular carcinoma (HCC) and portal vein tumor thrombosis (PVTT) generally have poor survival rates, but this study explored how combining conventional transarterial chemoembolization (cTACE) with hepatic arterial infusion chemotherapy (HAIC) affects outcomes.
  • In a retrospective evaluation of 155 patients, those receiving the combination treatment (cTACE-HAIC) showed significantly longer overall survival (9 months) and progression-free survival (6 months) compared to those who received cTACE alone (5 months and 2 months, respectively).
  • The study concluded that cTACE-HAIC is associated with better survival outcomes without increasing severe treatment-related side effects compared to cTACE alone.
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  • The study examines the effectiveness and safety of combining sorafenib with hepatic arterial infusion chemotherapy (HAIC) after transarterial chemoembolization (TACE) for patients with intermediate and advanced hepatocellular carcinoma (HCC).
  • Conducted as a phase II trial, sixty-six participants were treated with sorafenib followed by intra-arterial administration of chemotherapy agents, with safety and progression-free survival as key outcomes.
  • Results showed an objective response rate of 42.4% and a disease control rate of 87.9%, though some patients experienced significant toxicity, including grade 3-4 side effects like thrombocytopenia.
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Steroid estrogens, as typical endocrine disrupting chemicals (EDCs), have raised an increasing concern due to their endocrine disrupting effects on aquatic animals and potential hazards on human health. Batch experiments were conducted to study 17 beta-estradiol (E2) removal and Estradiol Equivalent Quantity (EEQ) elimination by anaerobic granular sludge (AnGS) combined with different valence iron sources. Results showed that E2 was effectively biodegraded and transformed into E1 by AnGS.

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Aims: This study aims to observe the preliminary clinical efficacy of percutaneous interstitial brachytherapy using iodine-125 seeds for the treatment of advanced malignant lung tumors.

Subjects And Methods: This retrospective study enrolled 24 patients in our hospital with advanced malignant lung tumors between June 2013 and November 2017. Computed tomography (CT)-guided iodine-125 seed implantation therapy was administered to these patients.

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