Gene SH3BGRL3 regulates acute myeloid leukemia progression through circRNA_0010984 based on competitive endogenous RNA mechanism.

Acute myeloid leukemia (AML) is a malignant proliferative disease affecting the bone marrow hematopoietic system and has a poor long-term outcome. Exploring genes that affect the malignant proliferation of AML cells can facilitate the accurate diagnosis and treatment of AML. Studies have confirmed that circular RNA (circRNA) is positively correlated with its linear gene expression.

NDRG3 regulates imatinib resistance by promoting β‑catenin accumulation in the nucleus in chronic myelogenous leukemia.

Imatinib resistance in chronic myelogenous leukemia (CML) is a clinical problem. The present study examined the role of N‑Myc downstream regulatory gene 3 (NDRG3) in imatinib resistance in CML. Quantitative PCR demonstrated that NDRG3 was highly expressed in patients with CML.

[Size Distribution and Source Appointment of Road Particles During Winter in Tianjin].

The significant role of traffic emissions mixed from various sources in urban air pollution has been widely recognized. However, the corresponding contributions to the roadside particle distribution are poorly understood due to the mixed impacts of various sources. Particle number concentrations of different sizes at the roadside in Nankai District of Tianjin were continuously monitored using a portable aerosol particle spectrometer during the morning rush hour (07:30-09:20) from Nov.

Characteristics of PM in an Industrial City of Northern China: Mass Concentrations, Chemical Composition, Source Apportionment, and Health Risk Assessment.

Urban and suburban PM samples were collected simultaneously during selected periods representing each season in 2019 in Zibo, China. Samples were analysed for water-soluble inorganic ions, carbon components, and elements. A chemical mass balance model and health risk assessment model were used to investigate the source contributions to PM and the human health risks posed by various pollution sources via the inhalation pathway.

Aircraft-based observation of gaseous pollutants in the lower troposphere over the Beijing-Tianjin-Hebei region.

To investigate the spatial and vertical distribution of atmospheric pollutants (SO, NO, CO and O), aircraft-based measurements (model: Yun-12, 12 flights, 27 h total flight time) were conducted from near the surface up to 2400 m over the Beijing-Tianjin-Hebei (BTH) region between June 17th and July 22nd 2016. The results showed that high concentrations of primary gaseous pollutants (SO, NO, CO) were generally present in Beijing, Tianjin, Langfang and Tangshan areas, while high values of O frequently appeared in areas far from the city. The flights at noon and dusk measured higher O concentrations at 600 m and lower O concentrations at higher altitudes, implying a strong influence by photochemical production.

Chemical Characteristics of Atmospheric PM and PM at a Rural Site of Lijiang City, China.

Emissions from biomass burning are very serious in Southeast Asia and South Asia in April. In order to explore the effect of long-range transport of biomass emissions from the Indochina Peninsula in Southwest China during the period of the southeast monsoon season and to find out the main pollution sources in local atmospheric PM, a field campaign was conducted from 6-26 April 2011 in Lijiang, China. Twenty-four-hour PM and PM filter samples were collected, and inorganic ions, elements, and carbonaceous components (including organic carbon (OC) and elemental carbon (EC), polycyclic aromatic hydrocarbons (PAHs) and nitrated PAHs (NPAHs)) were measured.

Chemical characteristics of road dust PM fraction in oasis cities at the margin of Tarim Basin.

In order to understand the compositions characteristics of particulate matter with aerodynamic diameter less than 2.5 μm (PM) fraction in road dust (RD) of oasis cities on the edge of Tarim Basin, 30 road dust (RD) samples were collected in Kashi, Cele, and Yutian in the spring, 2018, and RD was collected using the resuspension approach. Eight water-soluble ions, 39 trace elements and 8 fractions of carbon-containing species in PM were analyzed.

Vertical distribution of volatile organic compounds conducted by tethered balloon in the Beijing-Tianjin-Hebei region of China.

Volatile organic compounds (VOCs) as precursors of ozone and secondary organic aerosols can cause adverse effects on the environment and human health. However, knowledge of the VOC vertical profile in the lower troposphere of major Chinese cities is poorly understood. In this study, tethered balloon flights were conducted over the juncture of Beijing-Tianjin-Hebei in China during the winter of 2016.

[Distribution Characteristics and Source Apportionment of Elements Bonded with PM and PM in Linyi].

To investigate the pollution characteristics and sources of elements bonded with PM and PM in Linyi, PM and PM sample collections were carried out simultaneously in Linyi from December 2016 to October 2017, and 23 elements were determined by inductively coupled plasma mass spectrometry (ICP-MS) and inductively coupled plasma optical emission spectrometry (ICP-OES), with the enrichment factor method and PMF employed to determine the source apportionment. The results indicated that the dominant elements in PM and PM were recognized as Si, Ca, Al, Fe, K, Na, and Mg, accounting for 92.93% and 94.

[Emission Characteristics of Exhaust PM and Its Carbonaceous Components from China Ⅲ to China Ⅳ Diesel Vehicles in Shenyang].

Diesel vehicles were the primary source of atmospheric particulate matter (PM) emitted by motor vehicles. To study the emission factors and carbon components of PM and PM from diesel vehicles in Shenyang, exhaust PM samples were collected from 15 diesel vehicles including small, medium, and large passenger vehicles, and light, medium, and heavy-duty trucks under China Ⅲ and China Ⅳ emission standards. This was undertaken using a dilution channel sampling system, and the carbon components were also analyzed.

[Characterization of PM and PM Source Profiles for Emissions from Nonmetal Mineral Products Manufacturing Processes].

In view of the insufficient source profiles for emissions from nonmetal mineral products manufacturing processes in China, a dilution sampling system was used to collect PM and PM samples from glassmaking, ceramics, and firebrick manufacturing sources between February and June of 2017. The characteristics of 50 chemical components in the samples were studied to identify source profiles. The results showed that the dominant composition of particulate matter in glassmaking plant profiles was Na, with percentages ranging from 9.

A seriously sand storm mixed air-polluted area in the margin of Tarim Basin: Temporal-spatial distribution and potential sources.

In order to analyze the temporal-spatial distribution characteristics of PM, PM, SO, NO, CO and O in five cities and the potential sources of PM in southern Xinjiang during 2016, we collected one year officially released data for analysis. The average PM, PM SO, NO, O and CO concentrations were 289 ± 363, 99 ± 106, 17 ± 9, 29 ± 11, 65 ± 25 μg m and 1.3 ± 0.

Emission factors of polycyclic aromatic hydrocarbons from domestic coal combustion in China.

Domestic coal stove is widely used in China, especially for countryside during heating period of winter, and polycyclic aromatic hydrocarbons (PAHs) are important in flue gas of the stove. By using dilution tunnel system, samples of both gaseous and particulate phases from domestic coal combustion were collected and 18 PAH species were analyzed by GC-MS. The average emission factors of total 18 PAH species was 171.

[Effect of astragalus injection on U937 leukemia cells proliferation and apoptosis and relevant molecular mechanisms].

Objective: To study the effect of astragalus injection on U937 leukemia cells proliferation and apoptosis and relevant molecular mechanisms.

Methods: Leukemia cell line U937 cells were treated with different concentrations of astragalus (62.5, 125, 250, 500, 1 000 μg/mL).

Theoretical study on the reaction mechanism of ozone addition to the double bonds of keto-limonene.

The reaction mechanism of ozone (O3) addition to the double bonds of gas phase keto-limonene was investigated using ab initio methods. Two different possibilities for O3 addition to the double bond were considered and two corresponding van der Waals complexes (Complex 1 and Complex 2) were found for 1-endo and 2-endo. The rate constants were calculated using the transition state theory at the CCSD(T)/6-31G(d) + CF//B3LYP/6-31G(d,p) level.