A baseline decomposition ultra-short baseline localization algorithm for arbitrary array structures.

With the rapid development of the marine economy, hydroacoustic positioning technology plays an increasingly important role in marine engineering. The ultra-short baseline (USBL) hydroacoustic positioning system has the advantages of small size, simple operation, and flexible use, and has been widely used. Aiming at the existing USBL acoustic positioning algorithm with low positioning accuracy and complex calculation, a baseline decomposition localization algorithm with arbitrary array structure is proposed.

A D* orthogonal matching pursuit algorithm for time-varying channel estimation.

Orthogonal matching pursuit (OMP) combined with the A* search algorithm (A*OMP) exhibits robust reconstruction capabilities for synthesizing sparse data and signals, achieving relatively low reconstruction errors and a higher exact recovery ability than conventional OMP. However, A*OMP is only suitable for static channel estimation and cannot be applied to dynamic scenarios. This is because the channel delays for several consecutive orthogonal frequency-division multiplexing blocks per frame are similar and the path gains exhibit temporal correlation.

Smac/DIABLO regulates the apoptosis of hypertrophic scar fibroblasts.

In abnormal skin wound healing, hypertrophic scars (HS) are characterized by excessive fibroblast hypercellularity and an overproduction of collagen, leading to atypical extracellular matrix (ECM) remodeling. Although the exact mechanisms of HS remain unclear, decreased HS fibroblast (HSFB) apoptosis and increased proliferation are evident in the development of HS. In this study, the contribution of the second mitochondria-derived activator of caspases/direct inhibitor of apoptosis protein (IAP)-binding protein with a low isoelectric point (pI) (Smac/DIABLO), an apoptosis-promoting protein released from the mitochondria, was investigated in human normal skin and HSFB cultures.

The -2T/C polymorphism in the adrenocorticotropin receptor gene affects stress perception of patients with alopecia areata.

Background: Altered hypothalamic-pituitary-adrenal (HPA) axis response involved in the pathogenesis of stress-associated alopecia areata (AA) has been reported. A novel polymorphism -2T>C of the adrenocorticotropin receptor (ACTHR) can result in an insufficient HPA response to stress; therefore, the functional polymorphism may underlie a role in stress-associated AA.

Objective: To investigate the relationship between psychosocial factors and the risk of developing AA and to detect the association between the -2T>C polymorphism of ACTHR and AA.

An implication for post-transcriptional control: reciprocal changes of melanocortin receptor type 2 mRNA and protein expression in alopecia areata.

Alopecia areata (AA) is a hair follicle-specific autoimmune disease that is inherited genetically but triggered environmentally. Stress response is believed to play a role in the pathogenesis of AA. The hypothalamic-pituitary-adrenal axis (HPA axis), known as the stress axis, plays a cardinal role in the stress response.

Melanocortin receptor type 2 (MC2R, ACTH receptor) expression in patients with alopecia areata.

Human skin expresses elements of the hypothalamo-pituitary-adrenal (HPA) axis that function as a local stress response system. Because adrenocorticotropic hormone (ACTH) is an intermediate in the HPA axis from corticotropin-releasing hormone (CRH) signal to cortisol secretion, MC2R that binds only ACTH may be important in the stress response of skin. We investigated the local expression of MC2R by immunohistochemistry to identify the role of ACTH/MC2R in stress-associated alopecia areata (AA).

Expression of PPARgamma and Cbfalpha1 mRNA in bone marrow cells in Type 2 diabetic rats and its correlation with impaired fracture healing.

Objective: To investigate the relationship between impaired fracture healing and the expression of peroxisome proliferator activated-receptor gamma (PPARgamma) and core binding factor alpha 1 (Cbfalpha1) mRNA in the bone marrow of Type 2 diabetic rats.

Methods: Thirty male Sprague-Dawley rats were divided into a control group (n=15, normal diet) and an experiment group (n=20, high fat and sucrosum diet). After 8 weeks, one eyeball was culled for blood collection.