Publications by authors named "Baoen Zhang"
The ubiquitinproteasome system (UPS) is the main mechanism responsible for the intracellular degradation of misfolded or damaged proteins. Under inflammatory conditions, the immunoproteasome, an isoform of the proteasome, can be induced, enhancing the antigen-presenting function of the UPS. Furthermore, the immunoproteasome also serves nonimmune functions, such as maintaining protein homeostasis and regulating signalling pathways, and is involved in the pathophysiological processes of various cardiovascular diseases (CVDs).
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- This meta-analysis examines how coronary calcification affects the diagnostic accuracy of CT-derived fractional flow reserve (CT-FFR) and coronary computed tomography angiography (CCTA) across different levels of coronary artery calcium scores (CACS).
- The study included ten articles, comparing the diagnostic performance of CT-FFR and CCTA against invasive fractional flow reserve, with CT-FFR showing better accuracy in lower CACS groups (CACS < 400).
- The findings suggest that CT-FFR is more effective in detecting significant blockages in coronary artery disease patients with lower coronary artery calcium scores, making it a potential alternative to invasive angiography.