Publications by authors named "Baodi Li"

Avian H7N9 influenza virus, which emerged in 2013 China, had caused the fifth wave of peaks in 2016-2017. Gansu Province locate in western China far away from the epicenter of the virus, also detected cases in this wave. During the monitoring, five human cases with H7N9 virus infection, three cases in Jiuquan and two cases in Zhangye, were reported and investigated.

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After no reported human cases of highly pathogenic avian influenza (HPAI) H7N9 for over a year, a case with severe disease occurred in late March 2019. Among HPAI H7N9 viral sequences, those recovered from the case and from environmental samples of a poultry slaughtering stall near their home formed a distinct clade from 2017 viral sequences. Several mutations possibly associated to antigenic drift occurred in the haemagglutinin gene, potentially warranting update of H7N9 vaccine strains.

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Three main surveillance systems (laboratory-confirmed, influenza-like illness (ILI) and nationwide Notifiable Infectious Diseases Reporting Information System (NIDRIS)) have been used for influenza surveillance in China. However, it is unclear which surveillance system is more reliable in developing influenza early warning system based on surveillance data. This study aims to evaluate the similarity and difference of the three surveillance systems and provide practical knowledge for improving the effectiveness of influenza surveillance.

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Article Synopsis
  • The study investigated human rhinovirus (HRV) prevalence among children with acute respiratory infections in Gansu Province, collecting 286 throat swabs during 2011.
  • Out of these, 27 samples tested positive for HRV, with a notable positive rate of 9.44%, and most affected children were under one year old.
  • Genotype analysis revealed HRV A was the predominant strain, making up 84.62% of cases, indicating a variety of HRV genotypes circulated throughout the year, particularly affecting young children.
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