Publications by authors named "Baocheng Wan"
Article Synopsis
- Researchers found that lactate from glycolysis contributes to histone lactylation, impacting gene regulation in various tissues, but its role in the hypothalamus is not well understood.
- In a study, deleting the Fam172a gene in specific hypothalamic neurons (POMC neurons) increased histone lactylation, helping protect mice from diet-induced obesity.
- Conversely, overexpressing Fam172a led to obesity-like traits, demonstrating the crucial role of lactate and Fam172a in metabolic regulation in relation to obesity.
Global health concerns about micro- and nanoplastics are increasing. The newly discovered beige adipocytes play a vital role in energy homeostasis through their high thermogenic capacity upon activation. However, the effects of micro- and nanoplastics on beige adipocytes have not yet been studied.
View Article and Find Full Text PDFNeuregulin 4 (Nrg4) is an adipose tissue-enriched secreted factor that modulates glucose and lipid metabolism. Nrg4 is closely associated with obesity and preserves diet-induced metabolic disorders. However, the specific mechanisms via which Nrg4 regulates metabolic homeostasis remain incompletely understood.
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