Anti-aging derivatives of cycloastragenol produced by biotransformation.

In this study, the microbial transformation of cycloastragenol (CA) by the fungi AS 3.2456 and AS 3.407 yielded 19 metabolites.

Biotransformation of betulin by Mucor subtilissimus to discover anti-inflammatory derivatives.

Biotransformation of lupane-type triterpenoid betulin was carried out with Mucor subtilissimus CGMCC 3.2456. Yielded nine previously undescribed hydroxylated compounds.

Microbial transformation of the anti-aging agent cycloastragenol by .

The microbial transformation of cycloastragenol (CA) by AS 3.20 was investigated. Seven isolated products were identified as (20,24)-3β,6α,16β,25- tetrahydroxy-20,24-epoxy-9,10--cycloartan-9(11),10(19)-diene (), (20,24)- 3β,6α,16β,25-tetrahydroxy-20,24-epoxy-9,10--cycloartan-1(10),9(11)-diene (), (20,24)-3β,16β,25-trihydroxy-6α,19α;20,24-diepoxy-9,10--cycloartan-9(11)-ene (), (20,24)-6α,16β,25-trihydroxy-3β,10β;20,24-diepoxy-9,10-- cycloartan-11-one (), (20,24)-16β,25-dihydroxy-6α-methoxy-3β,10β;20,24- diepoxy-9,10--cycloartan-7(8),9(11)-diene (), (20,24)-6α,16β,25-trihydroxy-3β,10β;20,24-diepoxy-9,10--cycloartan-9(11)-ene (), and (20,24)-3β,6α,16β,25-tetrahydroxy-19-acetoxy-ranunculan-9(10)-ene () by spectroscopic analysis.

Anti-Inflammatory 18β-Glycyrrhetinin Acid Derivatives Produced by Biocatalysis.

In this study, the biocatalysis of 18-glycyrrhetinic acid by two strains of filamentous fungi, namely AS 3.2893 and AS 3.2695, was investigated.

Biotransformation of 20()-panaxatriol by the fungus Link AS 3.3950.

Microbial transformation of 20()-panaxatriol by the fungus Link AS 3.3950 was performed. Four new (-), along with two previously reported metabolites ( and ), were obtained.

MutL homolog 1 expression in thyroid carcinoma and its clinical significance.

Objective: The aim of this study was to evaluate the MutL homolog 1 (MLH1) protein expression in thyroid cancer patients and its association with clinical pathological characteristics.

Materials And Methods: Forty thyroid cancer tissues and 22 partial paired normal thyroid tissues from 40 thyroid cancer patients who received surgery were collected in this study. MLH1 protein expression was tested by immunohistochemical method for the 40 cancer tissues and 22 partial paired normal thyroid tissues.

Laparoscopic versus open total gastrectomy for advanced proximal gastric carcinoma: a matched pair analysis.

Purpose: Laparoscopic total gastrectomy for advanced proximal gastric carcinoma is a complex and challenging procedure, limited to a few expert centers. This study analyzed the short- and long-term outcomes of laparoscopic total gastrectomy for advanced proximal gastric carcinoma compared with open gastrectomy.

Methods: From January 2008 to January 2015, 61 patients underwent laparoscopic total gastrectomy for advanced proximal gastric carcinoma.

Determination of the intrinsic reactivities for carbon dioxide gasification of rice husk chars through using random pore model.

Rice husk is abundantly available and environmentally friendly, and char-CO2 gasification is of great importance for the biomass gasification process. The intrinsic reaction rates of carbon dioxide gasification with rice husk chars derived from different pyrolysis temperatures were investigated in this study by conducting thermogravimetric analysis (TGA) measurements. The effects of gasification temperature and reactant partial pressure on the char-CO2 gasification were investigated and the random pore model (RPM) was used to determine the intrinsic kinetic parameters based on the experimental data.