Publications by authors named "Bao-xing Liu"

The occurrence of varicocele infertility can be attributed to the small and flexural spermatic plexus which constitutes the main structure of spermatic cord.Obstruction of blood circulation, stagnation of qi and blood, ultimately leading to infertility. The spermatic plexus ' physiological and pathological symptoms are consistent with the theory of visceral collateral.

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Male infertility is a common condition in urology with complex etiology. This article explores the understanding of male infertility through the theories of traditional Classic prescriptions based on the text "Jin Gui Yao Lue". The aim is to provide references for clinical diagnosis and treatment of male infertility.

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Objective: To observe the changes in semen parameters after COVID-19 infection and clarify its impact on male fertility.

Methods: We collected semen samples from 82 male patients infected with COVID-19 in the past 2 months (the infection group) and 14 normal healthy men (the control group), obtained their semen parameters and compared them between the two groups before and after COVID-19 infection.

Results: There were no statistically significant differences in the baseline semen parameters between the infection and control groups (P > 0.

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Article Synopsis
  • Erectile dysfunction (ED) in young men (ages 20-40) shares risk factors with cardiovascular disease, but the specific biochemical relationships haven’t been clearly defined yet.* -
  • A study involving 289 young ED patients and a control group of 1,155 non-ED individuals assessed various health markers, revealing significant differences in LDL cholesterol, blood glucose, and creatinine levels in the ED group.* -
  • The findings suggest that high LDL, blood glucose, and creatinine levels are associated with ED in young men, emphasizing the importance of monitoring these factors for potential risk.*
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Article Synopsis
  • Neoadjuvant chemotherapy (NAC) and neoadjuvant chemoradiotherapy (NACR) are standard treatments for esophageal squamous cell carcinoma (ESCC), but patient survival rates remain low, prompting research into immune checkpoint inhibitors (ICIs) as a potential new treatment option.
  • A two-arm phase III clinical trial is underway in Henan Cancer Hospital to compare the effectiveness of NAC versus NAC combined with the ICI toripalimab, focusing on event-free survival and several other patient outcomes over an 18-month patient recruitment period.
  • The trial aims to determine if adding toripalimab to NAC can improve treatment results for locally advanced resectable ESCC, potentially changing the way this cancer
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Background: Neoadjuvant therapy plus oesophagectomy has been accepted as the standard treatment for patients with potentially curable locally advanced oesophageal cancer. No completed randomized controlled trial (RCT) has directly compared neoadjuvant chemotherapy and neoadjuvant chemoradiation in patients with oesophageal squamous cell carcinoma (ESCC). The aim of the current RCT is to investigate the impact of neoadjuvant chemotherapy plus surgery and neoadjuvant chemoradiotherapy plus surgery on overall survival for patients with resectable locally advanced ESCC.

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Article Synopsis
  • The study aimed to evaluate the impact of electroacupuncture (EA) on cytoskeletal protein expression in Sertoli cells and sperm production in rats with a specific fertility issue called oligozoospermia.
  • Twenty healthy male rats were divided into four groups to compare normal conditions, treatment with a drug (tripterygium glycosides), a sham procedure, and actual EA treatment at specific acupuncture points over 30 days.
  • Results showed that EA treatment significantly improved sperm count and movement, increased specific proteins in Sertoli cells, and reduced cell death in germ cells compared to the other groups, indicating its positive effect on fertility.
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Objectives: Nil-by-mouth with enteral tube feeding is widely practised for several days after resection and reconstruction of oesophageal cancer. This study investigates early changes in postoperative gastric emptying and the feasibility of early oral feeding after thoracolaparoscopic oesophagectomy for patients with oesophageal cancer.

Methods: Between January 2013 and August 2013, gastric emptying of liquid food and the feasibility of early oral feeding after thoracolaparoscopic oesophagectomy was investigated in 68 patients.

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Background: Patients with osteonecrosis of the femoral head (ONFH) have a severe impact on their health status, functionality and quality of life. Sexual life is an important component of the quality of life and is still a frequently neglected domain in patients with ONFH. The aims of the study were to evaluate the influence of the disease and the total hip arthroplasty (THA) surgery on quality of sexual life (QSL) in these patients.

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Objective: To evaluate the effects of the Chinese herbal formula Wuzi Yanzong Pill (, WYP) on the spermatogenesis and specific secretory functions of Sertoli cells in rat model and to investigate the underlying mechanism.

Methods: Five groups of male Sprague-Dawley rats including the control group, the model group, the low-dose WYP group, the medium-dose WYP group and the high-dose WYP group (5 in each group) were treated daily with vehicle, multiglycosides of Tripterygium wilfordii Hook f (GTW) either alone (20 mg/kg) or followed by WYP (0.5, 1.

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Objective: To evaluate the safety and efficacy of thoraco-laparoscopic subtotal esophagectomy in the treatment of esophageal cancer.

Methods: Clinical data of 98 patients with esophageal cancer who underwent thoraco-laparoscopic subtotal esophagectomy from March 2009 to October 2011 were retrospectively analyzed. One hundred and five patients were served as controls who underwent open three-field subtotal esophagectomy in the same period.

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Erectile dysfunction (ED) is a major complication of diabetes mellitus. Icariin has been shown to enhance erectile function through its bioactive form, icarisid II. This study investigates the effects of icarisid II on diabetic rats with ED and its potential mechanism via the assessment of advanced glycosylation end products (AGEs), autophagy, mTOR and the NO-cGMP pathway.

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Objective: Cytokines such as VEGF and IGF play an important role in maintaining the function of blood vascular endothelium. And Akt1 is an important molecule in the intra-cellular signaling transduction. This study aims to investigate the molecular mechanism of Shugan Yiyang (SGYY) capsule in the treatment of arteriogenic erectile dysfunction (AED) by detecting the expressions and phosphorylation of VEGF, IGF and Akt1 in AED rats.

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Objective: To assess the mean age of sexual activity termination, the prevalence of erectile dysfunction (ED), and their related factors in the old male population in Beijing.

Methods: We included in this study 764 males aged over 60 years old received in the health examination clinic and investigated the prevalence of ED and the related factors using the sexual health assessment resource (SHARE) and IIEF-5 questionnaires.

Results: The average age of sexual activity termination (no sexual intercourse in over 2 years) was 68.

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Objectives: To determine the effectiveness of superselective cavernous artery embolization.

Methods: Eight patients with high-flow priapism were included in this study. All were treated by superselective cavernous artery embolization with microcoils and gelatin sponges.

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Aim: To determine whether cyclooxygenase-2 (COX-2) was expressed in human esophageal squamous cell carcinoma.

Methods: Quantitative reverse transcription-polymerase chain reaction (RT-PCR), western blotting, immunohistoc-hemistry and immunofluorescence were used to assess the expression level of COX-2 in esophageal tissue.

Results: COX-2 mRNA levels were increased by >80-fold in esophageal squamous cell carcinoma when compared to adjacent noncancerous tissue.

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