Long-term results of surgical treatment of aortic and mitral regurgitation with enlarged left ventricle.

Mitral valve and aortic valve regurgitation associated with enlarged left ventricle remains difficult to manage and the long-term results following surgical treatment is uncertain. Between April 1988 and September 2000, 82 patients with aortic and mitral regurgitation associated with enlarged left ventricle underwent valve replacement at Anzhen Hospital. The valve disease was rheumatic in origin in 75 patients (91.

In Vitro Screening for Antihepatic Steatosis Active Components within Coptidis Rhizoma Alkaloids Extract Using Liver Cell Extraction with HPLC Analysis and a Free Fatty Acid-Induced Hepatic Steatosis HepG2 Cell Assay.

A high-throughput method was developed and applied to screen for the active antihepatic steatosis components within Coptidis Rhizoma Alkaloids Extract (CAE). This method was a combination of two previously described assays: HepG2 cell extraction with HPLC analysis and a free fatty acid-induced (FFA) hepatic steatosis HepG2 cell assay. Two alkaloids within CAE, berberine and coptisine, were identified by HepG2 cell extraction with HPLC analysis as high affinity components for HepG2.

Double-perovskite magnetic La2NiMnO6 nanoparticles for adsorption of bovine serum albumin applications.

Double-perovskite La2NiMnO6 (LNMO) nanoparticles were synthesized by co-precipitation process, and the adsorption of bovine serum albumin (BSA) protein on these nanoparticles was carried out. The powder samples were annealed at 750, 850, 950, and 1,050°C, respectively. X-ray diffraction (XRD) results reveal that there are double perovskites and exhibit mixed orientations, without any impurity phases.

[Clinical application of redo coronary artery bypass grafting].

Objective: To determine the clinical characteristics and outcomes of redo CABG.

Methods: The outcomes of 42 consecutive patients who underwent redo CABG from January 2002 to December 2010 was analyzed. There were 29 males and 13 females, aging from 46 to 78 years old with a mean of (61.

[The early and middle-long term clinical results of surgical treatment for ventricular septal rupture].

Objective: To explore the way of promoting the efficacy of surgical treatment for ventricular septal rupture (VSR) after acute myocardium infarction in terms of perioperative and long term survival.

Methods: The clinic data of 37 VSR cases underwent surgical treatment from October 1994 to October 2007 were analyzed retrospectively. There were 24 male and 13 female, and the age was (63.

[Long-term results of surgical repair of ruptured sinus of aortic sinus aneurysm].

Objective: To summarize the clinic characteristics and effect of surgical repair of ruptured aortic sinus aneurysm.

Methods: From September 1997 to September 2007, 43 patients with ruptured aortic sinus aneurysm underwent surgical procedures. There were 32 male and 11 female patients.

[Effects of Huafenqinutang and vardenafil for treatment of chronic prostatitis/chronic pelvic pain syndrome with concomitant erectile dysfunction].

Objective: To evaluate the effects of Huafenqinutang combined with vardenafil for the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) with erectile dysfunction.

Methods: One hundred and thirty-eight cases diagnosed as CP/CPPS with erectile dysfunction were randomized into trial group (70 cases) and control group (68 cases) for treatment with Huafenqinutang for 8 weeks, and in the former group, vardenaffil was added since the fifth weeks. All the cases were evaluated according to NIH-CPSI and IIEF-5 scores at 4 weeks and 8 weeks, respectively.

[Research on extracting process for compound shenzhutiaozhi capsule].

Objective: The technics of optimal extraction for compound shenzhutiaozhi capsule is investigated in this study.

Methods: Orthogonal test were employed for selecting the optimum of extraction technics and the contents of oleanolic acid and salvianolic acid B were detected by TLC-scanning and HPLC, respectively.

Results: Five volume of 70% alcohol, extracting 3 times with half an hour for each time, and seven volume of water, extracting 3 times with half an hour for each time were considered the optimum extraction technics of Frugtus Ligustri lucid, Salvie miltiorrhizae as well as Reizaoma Atractylodis Macrocfphalae, respectively.

[Jingjielianqiao Decoction promotes leg ulcer healing in rabbits].

Objective: To study the effect of Jingjielianqiao Decoction in promoting leg ulcer in rabbits.

Methods: Nine adult male New Zealand albino rabbits with chronic leg ulcers were randomized into 3 groups, namely group A treated with Jingjielianqiao Decoction, group B with Shengjiyuhong Decoction, and group C with normal saline. Gross observation of the wounds was carried out regularly for evaluating the changes in the ulcerous area, depth and wound surface excretion.

[Effect of Jingjielianqiao decoction on healing of skin ulcer in rats].

Objective: To study the pharmacodynamics of Jingjielianqiao decoction in promoting the healing of skin ulcer in mice.

Methods: Mouse models of skin ulcer were established by inducing skin trauma and scald, respectively. The skin ulcer of the mice was treated with Jingjielianqiao decoction or recombinant human epithelial growth factor (rhEGF), and the ulcer area after treatment was compared between the two groups and with their respective self control.

[Effect of saikosaponins on epileptic rat electroenciphalogram].

Objective: To study the effect of saikosaponins on the electroencephalogram (EEG) of epileptic rats to evaluate its therapeutic effect against epilepsies.

Methods: Sixty 8-week-old healthy SD rats were randomized into normal control group (A), epileptic model group (B), lamotrigine group (C), and 3 saikosaponin groups of small, moderate and high doses (D, E, and F groups, respectively), with 10 rats in each group. Penicillin was used to induce epilepsy in the latter 5 groups, and the EEG and onset of epileptic seizures were observed in each group.

[Digital model of the theory of Yin and Yang in traditional Chinese medicine].

To construct a digital model of Yin and Yang of traditional Chinese medicine (TCM), computerized binary digital coding was used for decomposition and reconstruction of the theory of Yin and Yang, which proved to be a successful simulation of the major ingredients of the theory and suggested the possibility of digitalization of the fundamental theories in TCM.

[Mechanism of quercetin as an antidiarrheal agent].

Objective: To investigate the antidiarrheal mechanism of quercetin extracted from Psidium guajava L.

Methods: The effects of quercetin on the contractility of guinea pig ileum in vitro and on the peristaltic motion of mouse small intestine in vivo were observed, and the peak value of contractility and peristaltic distance recorded. The inhibitory effect of quercetin on the permeability of the abdominal capillaries was also observed.

Progress of intervention of renal interstitial fibrosis with Chinese traditional herbal medicine.

This article reviews the current status of progress in the research of renal interstitial fibrosis therapy using traditional Chinese herbal medicine, which exerts its therapeutic effect through inhibiting cytokine expression and fibroblast proliferation, inducing apoptosis of the renal myofibroblasts and other mechanisms.