Synopsis of recent research by authors named "Bao-You Xu"
- Bao-You Xu's research primarily focuses on the use of tilapia islets for xenotransplantation as a viable alternative to porcine islets, demonstrating that tilapia islets can be harvested cost-effectively and maintain long-term normoglycemia in diabetic models.
- Studies have shown that encapsulated tilapia islets, combined with recipient immunosuppression, can improve survival rates in islet transplantation for diabetes therapy, and that the absence of local autoantigens in grafts influences T-cell recruitment and graft rejection.
- Xu has also contributed to understanding glucose transport mechanisms in tilapia, focusing on the molecular characterization of glucose transporter 1 and the effects of glucose toxicity on islet xenotransplantation, further enhancing the knowledge base for diabetes treatment strategies.
