hMSH2 coordinated with the expression of E2F1 promotes platinum response in epithelial ovarian cancer.

Objective: To explore underlying mechanisms that regulate hMSH2 expression and drug susceptibility in epithelial ovarian cancer (EOC).

Methods: Using data from the Cancer Genome Atlas (TCGA) we used bioinformatical analysis to predict transcription factors (TFs) that potentially regulate hMSH2. RT-qPCR, Western blot, and luciferase assays were undertaken using ovarian cancer cell lines to verify the identified TF.

Prognostic implications of PPL expression in ovarian cancer.

Periplakin (PPL) is a main member in plakin family, which plays important role in cellular adhesion complexes supporting and cytoskeletal integrity supplying. PPL was reported to be a potential biomarker candidate for several types of cancers. However, the biological functions and underlying mechanisms of PPL in ovarian cancer (OV) remain unclear.

Research progress in self-oscillating polymer brushes.

Polymer brushes possess unique changes in physical and chemical properties when they are exposed to external stimuli and have a wide range of applications. Self-oscillating polymers are anchored on surfaces of certain materials and are coupled with some self-oscillating reactions (with the Belousov-Zhabotinsky (BZ) reaction as an example) to form self-oscillating polymer brushes. As an independent field of stimulus response functional surface research, the development of new intelligent bionic materials has good potential.

Contamination and transmission of Mycobacteria in indoor environments of public buildings.

Objectives: The aim of this study was to detect Mycobacterium tuberculosis complex, M. avium subsp. avium and M.

2D carboxylate-bridged Ln coordination polymers: displaying slow magnetic relaxation and luminescence properties in the detection of Fe, CrO and nitrobenzene.

Eight new 2D isostructural lanthanide coordination polymers (Ln-CPs), [Ln(HL)(HO)(NO)]·NO (1-Ln), Ln = Nd, Sm, Eu, Gd, Tb, Dy, Ho, and Yb ions, HL = 4-(3,5-dicarboxylphenyl)-2-methylpyridine, were synthesized by using solvothermal methods and studied by structural analyses, magnetic analyses and luminescent probes. Crystallographic studies revealed that these compounds are 2D frameworks in which dinuclear units with double μ-syn,syn-carboxylate bridges are interlinked by single μ-trans,trans-carboxylate bridges from organic spacers. The layers are further stabilized and combined into 3D architectures through intra- and interlayer ππ stacking interactions and hydrogen bonding, respectively.