Full Mouth Rehabilitation for a Patient with Angle's Class II Division 2 Associated Deep Overbite and Worn Dentition - Case Report With 2-Year Follow-Up and Literature Review.

Some of the critical clinical challenges encountered in the treatment of adult patients with deep overbite and worn dentition include correction of deep overbite, establishment of an appropriate occlusal vertical dimension (OVD), and maintenance of long-term occlusal stability. Although Angle's Class II division 2-associated deep anterior overbite is common in orthodontic treatment, simple prosthodontic treatment with great improvement of deep anterior overbite and worn dentition is infrequently reported. A 51-year-old man with Class II Division 2 malocclusion presented with hypo-divergent facial pattern, reduced lower facial height, and protuberant lips.

Stabilizing High-Valence Copper(I) Sites with Cu-Ni Interfaces Enhances Electroreduction of CO to C Products.

In this study, the copper-nickel (Cu-Ni) bimetallic electrocatalysts for electrochemical CO reduction reaction(CORR) are fabricated by taking the finely designed poly(ionic liquids) (PIL) containing abundant Salen and imidazolium chelating sites as the surficial layer, wherein Cu-Ni, PIL-Cu and PIL-Ni interaction can be readily regulated by different synthetic scheme. As a proof of concept, Cu@Salen-PIL@Ni(NO) and Cu@Salen-PIL(Ni) hybrids differ significantly in the types and distribution of Ni species and Cu species at the surface, thereby delivering distinct Cu-Ni cooperation fashion for the CORR. Remarkably, Cu@Salen-PIL@Ni(NO) provides a C2+ faradaic efficiency (FE) of 80.

Covalent Organic Frameworks Boost the Silver-Electrocatalyzed Reduction of CO: The Electronic and Confinement Effect.

The electrocatalytic reduction of CO to CO with high efficiency is one of the most promising approaches for CO conversion due to its considerable economic feasibility and broad application prospects. In this study, three Ag@COF-R (R = -H, -OCH, -OH) hybrids were facilely fabricated by impregnating silver acetate (AgOAc) into respective covalent organic frameworks (COFs) prepared in advance. They differ significantly in the crystallinity, porosity, distribution, size, and electronic configuration of AgOAc species, which thereby influences both the activity and the selectivity of electrolytic CO-to-CO transformation.

Fox transcription factor AccGRF1 in response to glyphosate stress in Apis cerana cerana.

Glyphosate is an herbicide commonly used in agriculture, and its widespread use has adversely affected the survival of nontarget organisms. Among these organisms, bees in particular are important pollinators, and declining bee populations have severely affected crop yields around the world. However, the molecular mechanism by which glyphosate harms bees remains unclear.

Honey bee larval culture : gut emptying determines the transition from larva to prepupa and recombinant AccApidaecin improves antibacterial activity.

rearing of honey bee larvae is ideal for bioassay studies; no honey bee stable cell lines are available. Inconsistency of internal development staging of reared larvae and a susceptibility to contamination are common problems encountered. Standardized protocols on rearing larvae to make the larvae growth and development more similar to that of natural colonies are necessary to ensure the accuracy of experimental results and promote honey bee research as a model organism.

Safety and Efficacy of Midface Augmentation Using Bio-Oss Bone Powder and Bio-Gide Collagen Membrane in Asians.

(1) Background: Asians tend to have a regressive midface. Midface augmentation is an effective treatment, and various materials have been used as fillers for this purpose. Bio-Oss bone powder has a strong positive effect on promoting new bone regeneration, and has been used in the dental field for over 30 years.

AmAtg2B-Mediated Lipophagy Regulates Lipolysis of Pupae in .

Lipophagy plays an important role in regulating lipid metabolism in mammals. The exact function of autophagy-related protein 2 (Atg2) has been investigated in mammals, but research on the existence and functions of Atg2 in (AmAtg2) is still limited. Here, autophagy occurred in honeybee pupae, which targeted lipid droplets (LDs) in fat body, namely lipophagy, which was verified by co-localization of LDs with microtubule-associated protein 1A/1B light chain 3 beta (LC3).

Sn-Ag Synergistic Effect Enhances High-Rate Electrocatalytic CO -to-Formate Conversion on Porous Poly(Ionic Liquid) Support.

The electrocatalytic transformation of carbon dioxide (CO ) to formate is a promising route for highly efficient conversion and utilization of CO gas, due to the low production cost and the ease of storage of formate. In this work, porous poly(ionic liquid) (PPIL)-based tin-silver (Sn-Ag) bimetallic hybrids (PPIL -Sn Ag ) are prepared for high-performance formate electrolytic generation. Under optimal conditions, an excellent formate Faradaic efficiency of 95.

Ruthenium-catalyzed reductive amination of ketones with nitroarenes and nitriles.

The Ru(dppbsa)-catalyzed reductive amination of ketones with nitroarenes and nitriles using H as the environmentally benign hydrogen surrogate is developed in this study. Cross-experiments demonstrated that both reactions are initiated by the reduction of nitroarenes or nitriles to the corresponding amines, followed by condensation with ketones to give imines and thereafter hydrogenation. However, the route to the formation of an amino-ligated Ru complex during the reduction of nitroarenes or nitriles, followed by nucleophilic C-N coupling, cannot be completely excluded.

Scalable Palladium-Catalyzed Alkoxycarbonylation of Conjugated Dienes.

The Pd(cod)Cl-catalyzed alkoxycarbonylation of conjugated dienes to β,γ-unsaturated esters was approached by both intramolecular phosphinesulfonate L and intermolecular PPh/PTSA in this study. However, the poor solubility of the Pd/L complex and the labile monodentate Pd/PPh structure restricts the system efficiency, especially for the scale-up application. By contrast, the stable and well-soluble bidentate Xantphos system allows for the quantitative formation of 3-pentenoate (96%) on a gram scale within 6 h in weakly alkaline -methylpyrrolidone (NMP), which also functions as a basic site to promote the rate-limiting alcoholysis step while reducing the dosage of ligand to a theoretical value.

Adjustment of W-O-Zr Boundaries Boosts Efficient Nitrilation of Dimethyl Adipate with Ammonia on WO/ZrO Catalysts.

In this study, a tungstated zirconia (WO/ZrO) catalyst was developed for the continuous synthesis of adiponitrile (ADN) by gas-phase nitrilation of dimethyl adipate (DMA) with NH. The highest TOF could be reached on WO/ZrO bearing ∼1D WO species (highly dispersed and discontinuous status) at the surface, which, however, delivered the poorest selectivity toward nitrilation (S). In comparison, both efficient and selective transformation of DMA to ADN was achieved by fabricating WO/ZrO with continuously distributed oligomeric WO species (∼2D) at the surface, either by varying the dosage of the W-reagent in the preparation of WO(m)/ZrO or by doping a proper amount of the Mn element into WO(5.

[Corrigendum] Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord.

Subsequently to the publication of this paper, an interested reader drew to the authors' attention that, in Fig. 3 on p. 4973, the data panels shown for the "Osteogenesis" row of data for the GMSC and BMSC experiments appeared to be overlapping, such the data may have been derived from the same original source.

Rhodium(III)-Catalyzed Triple Aryl/Alkenyl C-H Bond Activation of Aryl Enaminones to Access Naphtho[1,8-]pyrans.

Rhodium(III)-catalyzed triple C-H bond activation of aryl enaminones was achieved to access naphtho[1,8-]pyrans by oxidative annulation to internal alkynes. 1-Naphthols might be formed as the only products, depending on the steric and/or electronic environment around the aroyl moiety of the aryl enaminones or the electronic impact from the alkynes. With propargyl alcohols as the masked terminal alkynes, aryl enaminones underwent rhodium(III)- or rhodium(I)-catalyzed internal alkenyl C-H bond activation to afford functionalized but-2-ene-1,4-diones.

Tunable Construction of Multisubstituted 1,3-Dienes and Allenes a 1,4-Palladium Migration/Carbene Insertion Cascade.

Efficient palladium-catalyzed vinylic C-H alkenylation and allenylation of -disubstituted ethylenes with -tosylhydrazones of aryl alkyl and diaryl ketones were achieved to access trisubstituted 1,3-dienes and tetrasubstituted allenes, respectively. An aryl to vinyl 1,4-palladium migration/carbene insertion/β-hydride elimination sequence proceeded to switch the chemo- and regioselectivities to give structurally diverse products. Use of 2-FCHOH additive enables enhancement of the reaction efficiency through accelerating the key 1,4-palladium migration process.

Effect of posaconazole on the concentration of intravenous and oral cyclosporine in patients undergoing hematopoietic stem cell transplantation.

Purpose: This study aimed to investigate the interactions between posaconazole (POS) and intravenously/orally administered cyclosporine A (CsA) in allogeneic hematopoietic stem cell transplant (HSCT) recipients.

Methods: We included 118 allogeneic HSCT patients who received CsA and POS simultaneously between January 2017 and June 2020 in this study. The ratio of CsA blood concentration (ng/mL) to dosage (mg/day) (C/D) before and after POS initiation was compared.

Pi-inducedaggregation of sevelamer nanoparticles for vascular embolization.

Decades have witnessed rapid progress of polymeric materials for vascular embolic or chemoembolic applications. Commercially available polymeric embolics range from gelatin foam to synthetic polymers such as poly(vinyl alcohol). Current systems under investigation include tunable, bioresorbable microspheres composed of chitosan or poly(ethylene glycol) derivatives,gelling liquid embolics with improved safety profiles, and radiopaque embolics that are trackable.

Role of c-Jun NH -terminal kinase-mediated mitogen-activated protein kinase pathway in response to pesticides in Apis cerana cerana.

The mitogen-activated protein kinase (MAPK) cascade pathway plays an important role in regulating stress responses. The function of the c-Jun NH -terminal kinase (JNK), a component of the MAPK cascade pathway, in Apis cerana cerana (Acc) remains unclear. Here, JNK was isolated and identified from Acc.

Copper-Catalyzed [4 + 1] Annulation of Enaminothiones with Indoline-Based Diazo Compounds.

A concise synthetic route to spiroindoline-fused -heterocycles was developed through copper-catalyzed [4 + 1] annulation using enaminothiones as donor-acceptor synthons. Both 3-diazoindolin-2-imines and 3-diazooxindoles were amenable to work as effective C1 building blocks. The reaction proceeds a copper-catalyzed cascade process involving the generation of copper(I) carbene and C-S/C-C bond formation.

Electroreduction of carbon dioxide to multi-electron reduction products using poly(ionic liquid)-based Cu-Pd catalyst.

Electrocatalytic reduction of CO (CORR) to multi-electron (> 2e) products provides a green and sustainable route for producing fuels and chemicals. Introducing the second metal element is a feasible strategy for "managing" the key intermediate on Cu-based materials to further improve the CORR catalytic performance. In this work, palladium, which promises the generation of CO, was introduced into the poly(ionic liquid)-based copper hybrid (Cu@PIL) to construct a novel Cu-Pd bimetallic electrocatalyst (Cu@PIL@Pd).