D-limonene (4-isopropenyl-1-methylcyclohexene) is an important compound in several citrus essential oils (such as orange, lemon, tangerine, lime, and grapefruit). It has been used as a flavoring agent and as a food preservative agent, with generally recognized as safe (GRAS) status. D-limonene has been well-studied for its anti-inflammatory, antioxidant, anti-cancer, and antibacterial properties.
View Article and Find Full Text PDFJ Nanosci Nanotechnol
September 2020
Two new -configuration based Zn(II) coordination polymers with formula [Zn(L)(2,2'-bipy)₂] (1) and [Zn₂(L)₂(4,4'-bipy)] (2) (H₂L = 4,4'-{[1,2-phenylenebis-(methylene)]bis(oxy)}dibenzoic acid, 2,2'-bipy= 2,2'-bipyridine and 4,4'-bipy= 4,4'-bipyridine) have been synthesized and characterized. Both the compounds had been used as possible luminescent sensors for detecting nitroaromatic compounds (NACs) and as photocatalysts to photodegrade methyl violet (MV) under UV irradiation. The sensing experiments indicated that 2 displayed selective sensing for m-nitrophenol (MNP) with lower limit of detection (LOD) of 1.
View Article and Find Full Text PDFBackground: Bronchial hyperresponsiveness (BHR) has not been extensively performed in preschool children, possibly because of the difficulty in cooperating with the tests. We sought to determine the usefulness and safety of methacholine bronchial provocation test (MCh-BPT) for BHR assessment in preschool children.
Methods: We recruited 252 preschool children (190 healthy and 62 with wheezing) who underwent MCh-BPT at baseline.
A simple and efficient synthesis of NBN-doped conjugated polycyclic aromatic hydrocarbons (such as diazaborinines) has been accomplished by a catalyst-free intermolecular dehydration reaction at room temperature between boronic acid and diamine moieties with yields up to 99 %. Polycyclic aromatic hydrocarbons with a six-membered NBN ring are a new class of aggregation-induced emissive luminogens. Extremely sensitive detection of ppb levels of TNT by phenyl naphthodiazaborinine is straightforward.
View Article and Find Full Text PDFAn unusual Cu(ii) coordination polymer [Cu(Him)(L)] (1) having a 4,4'-{[1,2-phenylene bis-(methylene)]bis(oxy)}dibenzoic acid ligand and an imidazole ligand possessing a 1D zig-zag chain was constructed and its magnetic behaviour was investigated, which indicated a magnetic phase transition below 25 K as well as long-range magnetic ordering.
View Article and Find Full Text PDFZhongguo Ying Yong Sheng Li Xue Za Zhi
March 2017
Objective: To investigate whether the phosphatidyl-inositol-3-kinase/protein kinase B(PI3K/Akt)pathway is involved in anti-arrhythmia of resveratrol on ischemia/reperfusion in rat hearts.
Methods: Forty male rats of normal ECG were randomly divided into 4 groups (=10):sham control (SC) group, ischemic/reperfusion (I/R) group, resveratrol (Res) group, PI3K inhibitor LY294002 (LY294002) group. The rat myocardial I/R injury model was established in vivo.
Luminescent metal-organic frameworks (LMOFs) containing fluorescent probes for the detection of pollutants such as organic solvents and heavy metals are becoming increasingly important, with lanthanide-MOF (Ln-MOF) materials receiving greater attention owing to the possibility of achieving fine-tuned luminescent properties. Herein, two unusual isostructural nanocage-based three-dimensional Ln-MOFs, 1-Ln (Ln=Tb, Eu), are constructed, using a new diisophthalate ligand with active Lewis basic triazole sites. Selective gas adsorption, especially the removal of CO from CH , a primary component of natural gas and biogas, is desirable in terms of both economic and environmental considerations.
View Article and Find Full Text PDFFollowing the publication of this article, an investigation conducted internally within our Department has revealed that the data published in Fig. 5a are not reproducible. Consequently, confidence in the conclusions drawn from the reported results in the paper has been undermined and, as a result, all authors involved have unanimously agreed to the retraction of this article.
View Article and Find Full Text PDFA new Zn metal-organic framework, [Zn (L) (DMA) ]⋅5 DMA (H L=[1,1':3',1''-terphenyl]-3,3'',5,5''-tetracarboxylic acid, DMA=dimethylacetamide), has been synthesized and characterized. The structure contains a three-dimensional 3,4,4,6-connected net with (4.6 ) (6 )(6 )(4 .
View Article and Find Full Text PDFThe cancer stem cell (CSC) theory suggests that cancer growth and invasion is dictated by the small population of CSCs within the heterogenous tumor. The aim of the present study was to elucidate the cause for chemotherapy failure and the resistance of CSCs to apoptosis. A total of ~2.
View Article and Find Full Text PDFZhongguo Ying Yong Sheng Li Xue Za Zhi
April 2016
Objective: To study the role of Notch1 signaling pathway in the myocardial protective effects of resveratrol pro-treatment after hepatic ischemia/reperfusion injury.
Methods: Thirty-six healthy male SD rats were randomly divided into 3 groups:sham control (SC) group, hepatic ischemic/reperfusion (HIR) group, and pro-treatment resveratrol (Res) group,12 rats in each group. After each group with hepatic ischemia 40 min reperfusion 2 h (SC group placing equal time), the left ventricular function including left ventricular pressure (LVP), left ventricular systolic pressure (LVSP) and its derivate (±dp/dt) was measured; the serum activities of creatine kinase isoenzyme (CK-MB) and lactate dehydrogenase (LDH) and tumor necrosis factorα(TNF-α) and interleukin-6(IL-6) were detected.
Zhongguo Ying Yong Sheng Li Xue Za Zhi
September 2014
Objective: To investigate the effects of ischemic postconditioning (IPTC) on the changes of matrix metalloproteinases-2 (MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) protein and mRNA levels in rat heart subjected to ischemia/reperfusion, and explore the mechanism by which IPTC protects myocardial interstitium following ischemic/reperfusion (I/R).
Methods: Twenty four healthy male SD rats were randomly divided into 3 groups (n = 8): sham control (SC) group, I/R group and IPTC group. The parameters of left ventricular function including left ventricular systolic pressure (LVSP) and its derivate (±dp/dt) were measured; the amount of myocardial collagen contents was determined by hydroxyproline quantification; the plasma activity of creatine kinase (CK) and lactate dehydrogenase (LDH) was detected; the protien levels of MMP-2 and TIMP-2 was measured by Western blot and the mRNA levels of MMP-2 and TIMP-2 was detected by real-time PCR.
Zhongguo Ying Yong Sheng Li Xue Za Zhi
January 2014
Objective: To investigate the effect of ischemic postconditioning on the expression of rat myocardium matris metalloproteinase-2 (MMP-2) induced by ischemia/reperfusion (I/R) and relationship between its expression and interstitium and the effect on left ventricular function.
Methods: Twenty-four rats were randomly divided into 3 groups (n = 8): sham control (SC) group, ischemic/reperfusion (I/R) group and ischemic postconditioning (IPTC) group. The left ventricular peak systolic pressure and its derivate (+/- dp/dt) were calculated; The amount of myocardium collagenous were determined; The vitality of superoxide dismutase (SOD) and content of malondialdehyde (MDA) of plasma were detected; The activity of myocardium MMP-2 was measured by Western blot and RT-PCR.
Bergenin, a -glucoside of 4-O-methyl gallic acid from , is a naturally antitussive and expectorant agent. A rapid and sensitive liquid chromatography tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the determination of the active component-bergenin, in rat plasma after oral administration of aqueous extract. The plasma samples were pretreated by protein precipitation with acetonitrile and chromatographic separation was achieved on a Diamonsil C column (150 mm×4.
View Article and Find Full Text PDFObjective: To develop a qualitative and quantitative determination of multiple components for quality control of Hugu Capsule, a composite prescription in TCM.
Methods: HPLC analysis was performed on a Kromasil C18 column (5.0 microm, 250 mm x 4.
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
August 2009
Objective: To investigate the relationship between apoptosis of myocardial cell in the rats with sepsis and the expressions of Toll-like receptor 4 (TLR4), tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) mRNA, and the protective effect of glutamine (Gln) against apoptosis of myocardial cell.
Methods: Rat model of sepsis was reproduced by peritoneal injection with lipopolysaccharide (LPS), and the animals were divided into control group, LPS group and Gln group. Rats in each group were further divided into four subgroups, 0, 6, 12 and 24 hours ( n =6).
Zhonghua Liu Xing Bing Xue Za Zhi
September 2007
Objective: To explore the application value of correspondence analysis in ecological study.
Methods: We adopted correspondence analysis method to analyze the relationship between the amount of food intake in some cities in China and the male gastric carcinoma mortality.
Results: According to scatter plots of row and column points, there were regional differences among the male gastric carcinoma mortality in different cities of China.
Aim: To characterize the correlation between severity of hepatopulmonary syndrome (HPS) and degree of hepatic dysfunction, and to explore how intestinal endotoxemia (IETM) affects the development of HPS in cirrhotic rats.
Methods: Male Wister rats were fed with a diet containing maize flour, lard, cholesterol, and alcohol and injected subcutaneously with CCl(4) oil solution every two days for 8 wk to induce typical cirrhosis and development of HPS. The animals were also given a nitric oxide (NO) production inhibitor, N(omega)-nitro-L-arginine methyl ester (L-NAME) intraperitoneally, and an iNOS inhibitor, aminoguanidine hydrochloride (AG) via gavage daily from the end of the 4th wk to the end of the 6th or 8th wk, or a HO-1 inhibitor, zinc protoporphyrin (ZnPP) intraperitoneally 12 h prior to killing.
Zhonghua Fu Chan Ke Za Zhi
November 2006
Objective: To discuss the clinical feasibility of hysterectomy that preserves the ascending branch and the ovarian branch of the uterine artery, and the effect on the ovary.
Methods: Fifty-two women who received hysterectomy with preservation of the ovaries, the so called divest due to benign gynecological disease were selected as the study group. It consisted of 35 patients who received subtotal-divest and 17 patients who received total-divest.