Publications by authors named "Bao-Fu Yu"

Background: The septum is often underdeveloped in East Asian populations, and traditional endogenous extension stents may not adequately fulfill the requirements for rhinoplasty. Herein, we present an innovative exogenous extension framework featuring a mortise and tenon structure specifically designed for East Asians.

Methods: This framework comprises a mushroom-shaped rib cartilage component and a lancet-shaped expanded polytetrafluoroethylene (ePTFE) element, which are interconnected through a mortise and tenon design.

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Background: Orofacial clefts represent the most prevalent form of craniomaxillofacial deformity. Genetic factors are particularly significant in the development of orofacial clefts. This study was to investigate genetic variation in patients with orofacial clefts.

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Technique: Nostril "Q" deformity is a common postoperative deformity in nasal alar reduction surgery, and there are no clinical reports on its correction. Based on the traditional Z-plasty technique, we designed an asymmetric Z-plasty technique to transfer the triangular mucosal flap inside the nasal cavity to the zone of notch deformity to correct the Q deformity.

Results: We included 12 patients in recent years in this study.

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Objective: To validate the feasibility of an innovative nasal lining-framework complex (NLFC) for reconstructing total nasal defects.

Study Design: Retrospective cohort study.

Methods: This NLFC is composed of forearm flap and support framework.

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Article Synopsis
  • The study focused on investigating mRNA expression and signaling pathways during the healing of diabetic foot ulcers using tibial cortex transverse distraction surgery.
  • Tissue samples were collected before and after the surgery, revealing a total of 2441 genes were significantly up-regulated and 3904 were significantly down-regulated postoperatively.
  • Key findings highlighted the roles of genes like HLA-DRB1, HLA-DRB5, and CXCL5 in processes such as neovascularization and peripheral nerve improvement, with significant pathway enrichments including adherens junctions and Wnt signaling pathways related to healing and inflammation.
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Background: The external nasal alar reduction can be associated with many complications, such as nostril malformation and significant scarring. The authors proposed a 3-part analysis method for the design of nasal alar reduction surgery with the aim of improving nasal alar morphology more precisely.

Methods: The 3-part analysis was based on the patient's flared nose, wide nasal base, and drooping ala, respectively.

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Objective: The aim of this study was to investigate the dynamic expression of the SMAD family during guided bone regeneration for the reconstruction of cranio-maxillofacial bone defects.

Methods: A swine model of guided bone regeneration was established with one side of the rib as the trauma group and the contralateral as control group. Periosteal and regenerative tissue specimens were harvested at 9 time points in the early, middle, and late phases, and were subjected to gene sequencing and tissue staining.

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Background: The repair of upper lip defects is difficult and can result in asymmetry. The authors have developed a postauricular scalp composite tissue for the repair of upper lip defects. Herein, the authors, present the feasibility of scalp composite tissue grafts for repairing of upper lip defects.

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Summary: Nasal reconstruction in pediatric patients is challenging and requires consideration of later nasal development. The authors introduce an innovative preauricular free flap pedicled with retrograde vascular (PFFPRV) for pediatric nasal reconstruction. In the PFFPRV technique, the retrograde superficial temporal vessels were used as the flap pedicle.

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Background: The repair of nasal alar defects is challenging for plastic surgeons, and there is currently no standard operation. Herein, the authors reported the clinical outcomes of a nasofacial groove pedicled flap for the reconstruction of alar defect.

Methods: This retrospective study included patients who underwent the nasofacial groove pedicled flap for the reconstruction of alar defect between January 2018 and June 2020.

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Background: Restricted ventilation is common after rhinoplasty with an endogenous extension stent. The authors proposed an exogenous extension stent concept for Asian rhinoplasty patients to avoid this problem. Herein, we introduce an innovative stent in rhinoplasty for Asians, which is an application of this concept.

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Background: Current strategies for correcting alar retraction mainly include cartilage grafting and composite grafting, which are relatively complicated and may produce injury to the donor site. Herein, we introduce a simple and effective external Z-plasty technique for correcting alar retraction in Asian patients with poor skin malleability.

Methods: Twenty-three patients were presented with alar retraction and poor skin malleability, and they were very concerned about the shape of the nose.

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Isolated congenital alar rim defects are extremely rare, and there has been no standard technique for the reconstruction of remarkable aesthetic deformity. Herein, we introduce a trifoliate flap for the correction of isolated congenital alar rim defects in pediatric patients. Fifteen cases undergoing nasal alar sulcus rotation flap surgery were analyzed retrospectively.

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Background: Guided bone self-generation with periosteum-preserved has successfully regenerated mandibular, temporomandibular and interphalangeal joint. The aim of this study was to investigate the dynamic changes of gene expression of periosteum which was involved in the guided bone self-generation.

Methods: Rib defects of critical size were created in mature swine with periosteum-preserved.

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Article Synopsis
  • Parry-Romberg syndrome is a rare disorder causing progressive facial atrophy, with unknown causes and mechanisms.
  • A 25-year-old woman diagnosed with the syndrome underwent whole exome sequencing, revealing mutations in the genes MTOR and DHX37, though these were also found in her unaffected twin sister.
  • The study highlights the need to consider additional factors, such as environmental influences, in understanding the clinical implications of genetic variants associated with the syndrome.
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Objective: Nasal tip hypertrophy is common in Asians, and its reshaping is very critical in rhinoplasty. For patients who refuse any implant placed in the nose, there are limited options for tip reshaping. Herein, we introduce a new procedure of nasal tip and alar groove plasty through external nasal cutting in Asians.

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Objective: To investigate the dynamic expression of NFAT family of periosteum in guided bone regeneration process.

Material And Methods: The swine ribs on one side were used as the trauma group and the contralateral side as the control group. After rib segment was removed, periosteum was sutured to form a closed cavity mimicking guided bone regeneration.

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Background: Pseudomonas aeruginosa is an opportunistic pathogen, and because of its specificity, its treatments appear tricky in postrhinoplasty infections with internal implants. This study summarizes the clinical characteristics and treatment of this type of infections to provide some reference for clinical work.

Methods: We retrospectively analyzed 10 patients who were diagnosed with a nasal infection of P.

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Article Synopsis
  • * A total of 15 patients were involved, with conditions primarily related to basal cell carcinoma and trauma, and all procedures were successful without complications like flap necrosis.
  • * Patients reported good satisfaction levels long-term, indicating that this flap technique is a viable alternative to using free flaps for eyelid reconstruction.
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Background: Chronic refractory wounds were common and the treatments were complicated for burn and plastic surgeons. This study was to investigate the bacterial distribution characteristics and bacterial drug resistance of chronic refractory wound secretions.

Methods: The authors retrospectively analyzed 425 patients with chronic refractory wound infection.

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Background: According to Tessier classification, number 1 and number 2 craniofacial clefts involve the nasal ala. Congenital nasal cleft is not common and is difficult for reconstruction. Notches in the medial one-third of either nasal ala are typical manifestations in these patients.

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Background: Obvious scar and deformities are commonly observed with incision anterior to the alar-facial groove in alar excision surgery. The authors explored modified sill and alar excision to correct wide alar base and flare synchronously and decreased incident of unacceptable scar and deformities in Asian patients.

Methods: The authors conducted a retrospective cohort study including 52 consecutive patients undergoing this surgery.

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Purpose: The study was to explore whether the 3-dimensional printing guiding plate system could facilitate the modified procedure for arthroscopic treatment of nondisplaced scaphoid nonunion.

Methods: Patients, diagnosed with scaphoid nonunion without displacement, were randomly assigned into two groups. In Group A, the 3-dimensional printing guiding plate system was used for guiding fixation during the surgery.

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Objective: To assess the effect and complications of tibial cortex transverse distraction (TCTD) in treating diabetic foot ulcers and draw attention to the concerning issues of this procedure.

Methods: This case series included 30 patients with diabetic foot ulcers from four centers. The ulcers had not healed after >6 months.

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Objective: To evaluate the feasibility of locked intramedullary nailing, rather than locking plate fixation combined with fibular allograft augmentation, for initial varus proximal humeral fractures.

Methods: This prospective pilot study enrolled patients with initial varus proximal humeral fractures that were treated with a locking intramedullary nail. Radiography was performed to evaluate fracture healing.

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