Effect of neuroticism on Chinese athletes' vigor: serial mediating roles of pre-competition anxiety and mind wandering.

Introduction: Vigor plays an important role in mental health, and it is closely related to sporting performance. Neuroticism can affect individual vigor, but its internal mechanism remains unclear. This study aims to examine the relationship between neuroticism and vigor, and the role of anxiety and mind wandering between the two.

Costs over benefits: mind wandering in sporting performance.

Introduction: Athletes' mind wandering during competition has positive and negative effects. The purpose of this study was to explore the reason for these bidirectional effects.

Methods: We recruited 51 athletes from China to take part in semi-structured interviews in which we explored their experiences of mind wandering in competition.

miR-4685-3p Alleviates Human Brain Microvascular Endothelial Cells Injury by Regulating MMP9.

Objective: Cerebral microbleeds (CMBs) are punctate hemorrhagic lesions within the brain parenchyma and are a classic manifestation of cerebral small vessel disease (CSVD). The primary objective of this study is to investigate the potential role of miR-4685-3p and underlying mechanisms by which miR-4685-3p modulates matrix metalloproteinase-9 (MMP9) in cerebral microvascular endothelial cell injury.

Methods: We employed high-throughput sequencing to screen for differentially expressed miRNAs in the peripheral blood of patients with CMBs and healthy controls.

Type IV collagen-derived angiogenesis inhibitor: canstatin low expressing in brain-invasive meningiomas using liquid chromatography-mass spectrometry (LC-MS/MS).

Purpose: Brain invasion in meningiomas is considered an indicator of more aggressive behavior and worse prognosis. But the precise definition and the prognostic role of brain invasion remains unsolved duo to lacking a standardized workflow of surgical sampling and the histopathological detection. Searching for molecular biomarker expression correlating with brain invasion, could contribute to establish a molecular pathological diagnosis without problems of subjective interobserver variation and deeply understand the mechanism of brain invasion and develop innovative therapeutic strategies.

Clinical Study on the Application of Preserved Urethral Mucosa at the Prostatic Apex in Transurethral Plasmakinetic Resection of the Prostate.

Objective: To explore the differences in the clinical efficacy, complications, and safety of transurethral plasmakinetic resection of the prostate (PKRP) by the conventional approach versus the approach preserving the urethral mucosa at the prostatic apex in the treatment of benign prostatic hyperplasia (BPH).

Methods: A total of 90 patients with PKRP admitted to the First Hospital of Qinhuangdao from December 2018 to March 2021 were selected and divided into a control group (conventional PKRP,  = 45) and an observation group (PKRP with preserved urethral mucosa at the prostatic apex,  = 45). The clinical efficacy, safety, and sexual function of the groups were evaluated using the patients' International Prostate Symptom Score (IPSS), quality of life (QoL), prostate volume, maximum flow rate (Qmax), post-void residual (PVR), blood loss, surgical resection efficiency, and surgical complication data.

Reducing Slip Risk: A Feasibility Study of Gait Training with Semi-Real-Time Feedback of Foot-Floor Contact Angle.

Slip-induced falls, responsible for approximately 40% of falls, can lead to severe injuries and in extreme cases, death. A large foot-floor contact angle (FFCA) during the heel-strike event has been associated with an increased risk of slip-induced falls. The goals of this feasibility study were to design and assess a method for detecting FFCA and providing cues to the user to generate a compensatory FFCA response during a future heel-strike event.

Preliminary Study of Vibrotactile Feedback during Home-Based Balance and Coordination Training in Individuals with Cerebellar Ataxia.

Intensive balance and coordination training is the mainstay of treatment for symptoms of impaired balance and mobility in individuals with hereditary cerebellar ataxia. In this study, we compared the effects of home-based balance and coordination training with and without vibrotactile SA for individuals with hereditary cerebellar ataxia. Ten participants (five males, five females; 47  ±  12 years) with inherited forms of cerebellar ataxia were recruited to participate in a 12-week crossover study during which they completed two six-week blocks of balance and coordination training with and without vibrotactile SA.

Retention Effects of Long-Term Balance Training with Vibrotactile Sensory Augmentation in Healthy Older Adults.

Vibrotactile sensory augmentation (SA) decreases postural sway during real-time use; however, limited studies have investigated the long-term effects of training with SA. This study assessed the retention effects of long-term balance training with and without vibrotactile SA among community-dwelling healthy older adults, and explored brain-related changes due to training with SA. Sixteen participants were randomly assigned to the experimental group (EG) or control group (CG), and trained in their homes for eight weeks using smart-phone balance trainers.

Automatically evaluating balance using machine learning and data from a single inertial measurement unit.

Background: Recently, machine learning techniques have been applied to data collected from inertial measurement units to automatically assess balance, but rely on hand-engineered features. We explore the utility of machine learning to automatically extract important features from inertial measurement unit data for balance assessment.

Findings: Ten participants with balance concerns performed multiple balance exercises in a laboratory setting while wearing an inertial measurement unit on their lower back.

Clinical observation of minocycline hydrochloride ointment in the treatment of early peri-implantitis.

To observe and analyze the therapeutic efficacy of minocycline hydrochloride ointment in the treatment of early peri-implantitis. A total of 180 patients with early peri-implantitis and treated at our hospital were enrolled. The patients were divided into control group and research group, with 90 patients in each group.

Effects of long-term vestibular rehabilitation therapy with vibrotactile sensory augmentation for people with unilateral vestibular disorders - A randomized preliminary study.

Background And Objective: This pilot study aimed to investigate the effects of incorporating vibrotactile sensory augmentation (SA) on balance performance among people with unilateral vestibular disorders (UVD).

Methods: Eight participants with UVD were recruited. Participants completed 18 balance training sessions across six weeks in a clinical setting.

[Soil ecological stoichiometry characteristics under different types of biological soil crusts in the hilly Loess Plateau region, China].

Biological soil crusts (biocrusts) play an important role in soil nutrient accumulation and cycling. We examined the relationship between soil nutrient characters and biocrusts types, with six typical types of biocrusts in the hilly Loess Plateau region, including light cyanobacterial crust, dark cyanobacterial crust, cyanobacterial with moss crust (mixed crusts), moss crust, Diploschistes spp. crust, and Nostoc commune crust.

Vibrotactile display design: Quantifying the importance of age and various factors on reaction times.

Numerous factors affect reaction times to vibrotactile cues. Therefore, it is important to consider the relative magnitudes of these time delays when designing vibrotactile displays for real-time applications. The objectives of this study were to quantify reaction times to typical vibrotactile stimuli parameters through direct comparison within a single experimental setting, and to determine the relative importance of these factors on reaction times.

Automatically Evaluating Balance: A Machine Learning Approach.

Compared to in-clinic balance training, in-home training is not as effective. This is, in part, due to the lack of feedback from physical therapists (PTs). In this paper, we analyze the feasibility of using trunk sway data and machine learning (ML) techniques to automatically evaluate balance, providing accurate assessments outside of the clinic.

[Effects of trampling disturbance on soil organic carbon fractions and mineralization potential of biological soil crusts in the Loess Plateau Region, China].

The experiment was conducted in the plots that had been enclosed for nearly 20 years in the hilly Loess Plateau region. The effects of trampling disturbance on the biological soil crust (biocrust) coverage, soil organic carbon (SOC), soil easily oxidizable carbon (SEOC), SOC mineralization amount and mineralization rate were investigated. The biocrust SOC mineralization potential after disturbance in different soil layers were simulated by a first-order kinetic equation.

Effects of long-term balance training with vibrotactile sensory augmentation among community-dwelling healthy older adults: a randomized preliminary study.

Background: Sensory augmentation has been shown to improve postural stability during real-time balance applications. Limited long-term controlled studies have examined retention of balance improvements in healthy older adults after training with sensory augmentation has ceased. This pilot study aimed to assess the efficacy of long-term balance training with and without sensory augmentation among community-dwelling healthy older adults.

Configurable, wearable sensing and vibrotactile feedback system for real-time postural balance and gait training: proof-of-concept.

Background: Postural balance and gait training is important for treating persons with functional impairments, however current systems are generally not portable and are unable to train different types of movements.

Methods: This paper describes a proof-of-concept design of a configurable, wearable sensing and feedback system for real-time postural balance and gait training targeted for home-based treatments and other portable usage. Sensing and vibrotactile feedback are performed via eight distributed, wireless nodes or "Dots" (size: 22.

Comparative phytotoxicity of Rac-metolachlor and S-metolachlor on rice seedlings.

The toxicity of Rac-metolachlor and S-metolachlor on rice (IIYou92, Oryza sativa L.) seedlings was determined and compared in a hydroponics experiment. The elongation of shoot, main root, and the number of lateral roots were inhibited in both Rac- and S-metolachlor treatments.

Pleiotropic action of renal cell carcinoma-dysregulated miRNAs on hypoxia-related signaling pathways.

The von Hippel-Lindau (VHL) gene is lost in ≈ 70% of all renal cell carcinomas (RCCs); however, increasing evidence supports the involvement of alternative mechanisms in the regulation of VHL expression, including suppression by microRNAs (miRNAs). miRNAs are small, noncoding RNA molecules that regulate gene expression through binding to target mRNAs. In this study, we found that miRNAs, which are dysregulated in cases of RCC, can target multiple members of RCC-related signaling pathways.

Exploring the role of miRNAs in renal cell carcinoma progression and metastasis through bioinformatic and experimental analyses.

Metastasis results in most of the cancer deaths in clear cell renal cell carcinoma (ccRCC). MicroRNAs (miRNAs) regulate many important cell functions and play important roles in tumor development, metastasis and progression. In our previous study, we identified a miRNA signature for metastatic RCC.

miRNA profiling for clear cell renal cell carcinoma: biomarker discovery and identification of potential controls and consequences of miRNA dysregulation.

Purpose: Renal cell carcinoma is the most common neoplasm of the adult kidney. Currently to our knowledge there are no biomarkers for diagnostic, prognostic or predictive applications for renal cell carcinoma. miRNAs are nonprotein coding RNAs that negatively regulate gene expression and are potential biomarkers for cancer.

Presacral extrarenal Wilms tumor in a child.

Objectives: Wilms tumor (WT) is one of the most common solid tumors in children. It also is the most frequent tumor found in the kidneys. In 5% of cases, it affects both kidneys simultaneously.

Two new C21 steroidal glycosides from Marsdenia tenacissima (ROXB.) WIGHT et ARN.

Two new C(21) steroidal glycosides, tenacissoside L (1), tenacissoside M (2), were isolated from the stems of Marsdenia tenacissima (ROXB.) WIGHT et ARN. Their structures were elucidated, respectively, by means of chemical and spectral data, including ESI-MS, HR-ESI-MS, 1D-NMR and 2D-NMR.

[A comparative study on experimental and mathematical analysis of mechanical properties of PFM].

In this study we compare the experimental and mathematical analyses of mechanical properties of PFM and analyze their correlation levels and inner links. Fifteen PFM specimens with different thickness ratio of metal to porcelain are made , with the shape of 26mm x 4mm x 1.5mm, and are divided into 5 groups, the metal thickness increases with 0.