Publications by authors named "Bao Phung"
Incidence and factors associated with PrEP discontinuation in France.
J Antimicrob Chemother
July 2024
Objectives: HIV pre-exposure prophylaxis (PrEP) is effective in preventing HIV, but some seroconversions occur due to poor adherence or PrEP discontinuation. Our objective was to estimate the incidence of PrEP discontinuation and describe the reasons and factors associated with discontinuations.
Methods: A retrospective cohort was conducted in three French hospitals between January 2016 and June 2022.
Introduction: Our objective was to determine the risk factors of a "severe/critical" form of COVID-19 in a cohort of people living with HIV-1 (PLWH1) followed in the Bichat University Hospital center in PARIS, FRANCE.
Methods: This study was an observational retrospective monocentric cohort of PLWH1 diagnosed with COVID-19 between February 1 st and November 31 st, 2020. Risk factors associated with "severe/critical" forms were determined using stepwise forward selection.
Room temperature vulcanized (RTV) silicone rubber filled with aluminum trihydrate (ATH) is substantially engaged in electrical outdoor insulation applications. The pristine silicone rubber is highly combustible. ATH filled silicone rubber offers excellent electrical insulation but lacks in providing adequate flame retardancy.
View Article and Find Full Text PDFBackground: Langerhans cell histiocytosis (LCH) is more common in children than adults and involves many organs. In children, the BRAF V600E mutation is associated with recurrent and high-risk LCH.
Methods: We collected paraffin blocks of 94 pediatric LCH patients to detect BRAF V600E mutation by sequencing.
Objectives: The principal outcome was to describe clinical characteristics of a transgender male-to-female (TGW) cohort followed for pre-exposure HIV prophylaxis (PrEP).
Introduction: Few efforts and preventive interventions have targeted transgender population, despite them being at great risk of HIV infection.
Methods: This was a retrospective transgender male-to-female (TGW) cohort followed for PrEP at Bichat Hospital Sexual Health Clinic between February 2016 and January 2019.
Article Synopsis
- - The study examines the health issues faced by HIV-infected transwomen compared to HIV-infected cisgender men, focusing on metabolic syndrome, thyroid, and adrenal functions.
- - Results showed that while the prevalence of metabolic syndrome was similar between the two groups, transwomen had significantly higher rates of subclinical hypothyroidism (12% vs. 3%) and adrenal insufficiency (20% vs. 8%).
- - The findings indicate that although hormonal consumption was common among transwomen, it did not affect antiretroviral drug effectiveness; however, regular assessment of thyroid and adrenal functions is recommended for this population.
Neisseria meningitidis sequence type 11 is an emerging cause of urethritis. We demonstrate by using whole-genome sequencing orogenital transmission of a N. meningitidis sequence type 11 isolate causing urethritis in a monogamous couple of men who have sex with men.
View Article and Find Full Text PDFObjectives: To assess, in a clinical cohort, the efficacy of switching current ART in virologically suppressed patients to a dolutegravir-based regimen, regardless of the genotypic susceptibility score (GSS).
Patients And Methods: This was an observational single-centre study assessing ART-treated patients with plasma viral load (pVL) <50 copies/mL who were switched to a dolutegravir-based regimen with 1 year of follow-up. PCR negative was defined as an undetected PCR signal.
Objective: To assess, in a clinical cohort, the efficacy of switching treatment in virologically-suppressed patients to tenofovir/emtricitabine/rilpivirine as a single-tablet regimen (STR) using the PCR signal of the viral load (VL) assay and plasma drug determination (C24h).
Patients And Methods: An observational single-centre study enrolling patients with VL<50 copies/mL initiating rilpivirine-based STR. C24h and VL were performed until W48 and W96 of STR, respectively.