Modulation of gene expression by thymoquinone conjugated zinc oxide nanoparticles arrested cell cycle, DNA damage and increased apoptosis in triple negative breast cancer cell line MDA-MB-231.

Nanomedicines include the area of science that combines the drugs or diagnostic molecules using nanotechnology approach to improve its ability to target specific cells or tissues. Zinc oxide (ZnO) nanoparticles are known for its non-toxicity, biocompatibility and biosafety. Thymoquinone (TQ) is used in the present study from the seeds of (Black cumin seed).