Publications by authors named "Banoth Chandrasekhar"

Breast cancer, the second leading global cause of death, affects 2.1 million women annually, with an alarming 15 percent mortality rate. Among its diverse forms, Triple-negative breast cancer (TNBC) emerges as the deadliest, characterized by the absence of hormone receptors.

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The Covid-19 associated mucormycosis (CAM) is an emerging disease affecting immunocompromised patients. Prevention of such infections using probiotics and their metabolites persist as effective therapeutic agents. Therefore, the present study emphasizes on assessment of their efficacy and safety.

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Low molecular weight antimicrobial polypeptides were extracted and purified from the young fresh leaves of Azadirachta indica (neem). The total protein extracted was precipitated with 15% TCA-Acetone. The total purified proteins yielded from the two extraction methods were 122.

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Lignocellulosic biomass such as agricultural and forest residues are considered as an alternative, inexpensive, renewable, and abundant source for fuel ethanol production. In the present study, three different pretreatment methods for rice straw were carried out to investigate the maximum lignin removal for subsequent bioethanol fermentation. The chemical pretreatments of rice straw were optimized under different pretreatment severity conditions in the range of 1.

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The present study explains computational methods to design thermostable horseradish peroxidase enzyme using the crystal structure available from Protein Data Bank (PDB ID: 6ATJ). Multiple mutations were introduced to the original enzyme and developed a model by using Modeler9.14.

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Article Synopsis
  • The study evaluates 15 yeast strains from toddy palm nectar for their probiotic potential, using Saccharomyces boulardii as the control.
  • Selected strains were tested for resistance to antibiotics, tolerance to gastrointestinal conditions, and their ability to adhere to intestinal cells.
  • The two best strains were identified as Pichia kudriavzevii OBS1 and Saccharomyces cerevisiae OBS2, with OBS2 showing potential antioxidant and anticancer properties, suggesting its use as a probiotic for therapeutic applications.
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