Patient journey during and after a pre-eclampsia-complicated pregnancy: a cross-sectional patient registry study.

Objectives: To gain insight into the patient journey through a pre-eclampsia-complicated pregnancy.

Design: Cross-sectional patient registry study.

Setting: Online patient registry initiated by the Preeclampsia Foundation.

Bacterial resistance and impetigo treatment trends: a review.

Impetigo is a common cutaneous infection that is especially prevalent in children. The prevalence of colonization and infection with resistant strains is continually increasing, forcing clinicians to reevaluate treatment strategies. Newer topical agents are effective in treating infections with resistant strains and may help minimize resistance and adverse effects from systemic agents.

Current sunscreen issues: 2007 Food and Drug Administration sunscreen labelling recommendations and combination sunscreen/insect repellent products.

The Food and Drug Administration (FDA) regulates sunscreens as over-the-counter drugs. This article describes sunscreen actives available in the United States, new developments available elsewhere, and the amendment to the FDA 1999 sunscreen monograph, released on August 27, 2007, which proposes a new grading system for ultraviolet B protection, a cap of the sunburn protection factor to 50+, and a 4-star grading of ultraviolet A protection. In addition, current data on combination sunscreen and insect repellent products are discussed.

Phase I study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in solid tumors.

Purpose: To establish the maximum tolerated dose of lonafarnib, a novel farnesyltransferase inhibitor, in combination with paclitaxel in patients with solid tumors and to characterize the safety, tolerability, dose-limiting toxicity, and pharmacokinetics of this combination regimen.

Experimental Design: In a Phase I trial, lonafarnib was administered p.o.

Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.

Arabidopsis thaliana is an important model system for plant biologists. In 1996 an international collaboration (the Arabidopsis Genome Initiative) was formed to sequence the whole genome of Arabidopsis and in 1999 the sequence of the first two chromosomes was reported. The sequence of the last three chromosomes and an analysis of the whole genome are reported in this issue.

Undermatching in humans to amount of reinforcement.

Human subjects were exposed to a concurrent-chain procedure in which amount of reinforcement in the terminal links was varied. The experimental procedure was designed to resemble as closely as possible animal operant procedures: verbal instructions were eliminated, the key-press operant response was shaped, and a "consummatory" response was required to receive reward. In addition to varying amount of reward, three different pairs of initial-link values in the concurrent chain were studied.